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High Purity 99% Pharm Intermediate Pirfenidone CAS 53179 -13-8

China High Purity 99% Pharm Intermediate Pirfenidone CAS 53179-13-8, Find details about China Pirfenidone, 53179-13-8 from High Purity 99% Pharm Intermediate Pirfenidone CAS 53179-13-8

Trademark
ty
Transport Package
Bag
Specification
25kg/bag
Origin
China
Trademark
ty
Transport Package
Bag
Specification
25kg/bag
Origin
China
High Purity 99% Pharm Intermediate Pirfenidone CAS 53179-13-8High Purity 99% Pharm Intermediate Pirfenidone CAS 53179-13-8High Purity 99% Pharm Intermediate Pirfenidone CAS 53179-13-8High Purity 99% Pharm Intermediate Pirfenidone CAS 53179-13-8High Purity 99% Pharm Intermediate Pirfenidone CAS 53179-13-8High Purity 99% Pharm Intermediate Pirfenidone CAS 53179-13-8Products Description

cas :53179-13-8
Purity:99% Min
Other Names:Pirfenidone
MF: C12H11NO
EINECS No.: 621-260-7
Grade Standard: Food Grade, Medicine Grade
Usage: Animal Pharmaceuticals

pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved  acyl hydroxylase activity.



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