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Factory Price CAS 33286 -22-5 Diltiazem Hydrochloride / Diltiazem HCl

China Factory Price CAS 33286-22-5 Diltiazem Hydrochloride / Diltiazem HCl, Find details about China 33286-22-5, CAS 33286-22-5 from Factory Price CAS 33286-22-5 Diltiazem Hydrochloride / Diltiazem HCl

Model NO.
33286-22-5
Mode of Transportation
by Express, Air, Sea
Trademark
Customizable
Transport Package
Aluminum Foil Bags/Cartons/Barrel
Specification
25kg/package
Origin
Cn
HS Code
2934999090
Model NO.
33286-22-5
Mode of Transportation
by Express, Air, Sea
Trademark
Customizable
Transport Package
Aluminum Foil Bags/Cartons/Barrel
Specification
25kg/package
Origin
Cn
HS Code
2934999090
Factory Price CAS 33286-22-5 Diltiazem Hydrochloride / Diltiazem HCl
Common Namediltiazem hydrochloride
CAS Number33286-22-5Molecular Weight450.979
Density1.26g/cm3Boiling Point594.4ºC at 760mmHg
Molecular FormulaC22H27ClN2O4S
Factory Price CAS 33286-22-5 Diltiazem Hydrochloride / Diltiazem HClDiltiazem hydrochloride is a calcium ion influx inhibitor (a slow channel blocker or calcium antagonist).

1 Pharmacology This product is a calcium ion channel blocker, and its effect is related to the inhibition of calcium ion influx when the myocardium and vascular smooth muscle are depolarized. This product can effectively expand the epicardial and subendocardial coronary arteries, relieve spontaneous angina or angina caused by ergonovine-induced coronary artery spasm; by slowing down heart rate and lowering blood pressure, reducing myocardial oxygen demand and increasing Exercise tolerance and relieve exertional angina pectoris. This product can relax vascular smooth muscles, decrease peripheral vascular resistance, and lower blood pressure; the degree of blood pressure reduction is related to the degree of hypertension, and normal blood pressure will only cause a slight decrease in blood pressure. This product has a negative inotropic effect and can slow down the conduction of the sinus node and the atrioventricular node.
2 Toxicology Carcinogenic, mutagenic and reproductive toxicity effects have been reported in rats taking this product for 24 months, and mice taking this product for 21 months have not found carcinogenic effects. In vitro bacterial experiments have not found mutagenic effects. Animal experiments confirmed that this product has no obvious effect on fertility.


Factory Price CAS 33286-22-5 Diltiazem Hydrochloride / Diltiazem HClFactory Price CAS 33286-22-5 Diltiazem Hydrochloride / Diltiazem HClFactory Price CAS 33286-22-5 Diltiazem Hydrochloride / Diltiazem HCl

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