L-Triiodothyronine/T3 Application:
* Promote gluconeogenesis,
* Increase utilization and mobilization of glycogen stores,
* Stimulate protein synthesis,
* Promote cell growth and differentiation,
* Aid in the development of the brain and CNS.
* Thyroid hormones play vital roles in regulating the body's metabolic rate, heart and digestive functions, muscle control, brain development and the maintenance of bones.
* Cytomel (T3) is also commonly combined with other fat loss agents in order to increase its overall effect, as it does work synergistically with other fat loss agents.

L-Triiodothyronine/T3 Effects:
1) Effects on Fat Metabolism:
T3 (or more specifically, thyroid hormones in general) are investigated for their interactions with fat mass since, in survey research, thyroid activity may be related to fat mass and BMI.  Some studies suggest a correlation whereas other suggest it does not exist for those with normal thyroid function.It is a contest field, as some studies do exist that suggest a relation even in those with normal thyroid function. These discrepancies may be due to the highly variable 'normal range' of thyroid hormones.
 
2) Effects on Muscle Tissue:
In obese subjects, a reduction in urinary nitrogen has been reported with T3 supplementation, and was additive to fasting's reduction in urinary nitrogen; suggesting a muscle preserving effect. These results have been replicated a short-term metabolic ward study at 100mcg daily, in four divided dosages. However, at least one study has noted an increase in urinary nitrogen after four weeks usage, in doses ranging from 0.36-1.01mcg/kg bodyweight.
 
3) Effects on Cognition:
Thyroid hormone status is correlated with cognition, and a lower level of thyroid hormones is related to depressive-like symptoms.
 
L-Triiodothyronine/T3 Dosage:
25-50 mcg initially (if cardiovascular disease is present, initial dose should be 10-20 mcg). Additional
doses may be given, to a total of at least 65 mcg/day (not to exceed 100 mcg/day). Doses should be at
least 4 hr but not more than 12 hr apart.
 
Cytomel (T3) does speed fat loss. As a guideline, for most 12.5 mcg/day is a conservative "supplement" sort of dosing that seems to have no detectable adverse effect on thyroid function at all.
25 mcg/day is a "supplement" sort of dosing that does have some inhibitory effect.
50 mcg/day is a reasonably conservative bb'ing sort of dose that, of course, is more inhibitory.
75 mcg/day is getting into more of a problem area;
100 mcg/day in many cases leads to loss of muscle size and strength.
 
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