Anti-HIV API Zidovudine USP42 Powder with CAS 30516-87-1

China Anti-HIV API Zidovudine USP42 Powder with CAS 30516-87-1, Find details about China Zidovudine, 30516-87-1 from Anti-HIV API Zidovudine USP42 Powder with CAS 30516-87-1

Basic Info.

Model NO.

Zidovudine

Usage

Pharm

Raw Material

30516-87-1

Transport Machine

Ordinary Goods Truck

Appearance

White Powder

Trademark

Recedar

Transport Package

Drum

Specification

99%

Origin

China

HS Code

1302

Model NO.

Zidovudine

Usage

Pharm

Raw Material

30516-87-1

Transport Machine

Ordinary Goods Truck

Appearance

White Powder

Trademark

Recedar

Transport Package

Drum

Specification

99%

Origin

China

HS Code

1302

Product Desciption

Anti-HIV API Zidovudine USP42 powder with CAS 30516-87-1

Product Name: Zidovudine
CAS: 30516-87-1
MF: C10H13N5O5
MW: 283.24
EINECS:
Product Categories: Amino Acids;Miscellaneous Natural Products;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;API's;Antiviral;HIV/AIDS/Related Products;API;VIOCIN
Chemical Properties Off White Crystalline Powder
Usage A potent and selective inhibitor of HIV-1 replication
Usage antibacterial
General Description Slightly off-white odorless powdery solid.
Air & Water Reactions Dust may form an explosive mixture in air. Water soluble. Hydrolysis occurs in strongly basic solutions .

Zidovudine is an antiviral drug with a chemical formula of C10H13N5O4. It is used in the treatment of AIDS or AIDS-related syndromes and immunodeficiency virus (HIV) infections. On March 19, 1987, the US Food and Drug Administration approved the drug for marketing. Zidovudine is the world's first anti-AIDS drug approved by the US FDA. It has become the most basic component of "cocktail" therapy because of its definite curative effect. It is highly active against retroviruses including human immunodeficiency virus (HIV) in vitro. In virus-infected cells, it is phosphorylated by cellular thymidine kinase to zidovudine triphosphate, which can selectively inhibit HIV reverse transcriptase, leading to the termination of HIV chain synthesis and preventing HIV replication.

Package	carton drum with two plastic bags inside
Net weight	25KG/Drum
Storage	Sealed in cool and dry place to avoid moisture and light
Shelf life	2 years when properly stored
Lead time	1~3 days after confirmation

TEST ITEMS	SPECIFICATIONS
Appearance	White to yellowish powder
Solubility	Sparingly soluble in water, soluble in alcohol.
Melting range	Between 121°C and 125°C
Specific rotation	+60.5°~+63°
	Corresponds to the IR spectrum of Zidovudine RS
Identification	Corresponds to the retention time of major peak in the chromatogram of the standard preparation
Water	NMT 1.0%
Residue on ignition	NMT 0.25%
Related Substances Test A
Method 1	Maximum unspecified impurity NMT 0.5%
	Total impurities NMT 3.0%
	Maximum unspecified impurity NMT 0.5%
Method 2	Triphenylmethanol NMT 0.5%
	Total impurities NMT 3.0%
Related substances Test B
Impurity B	NMT 1.0%
Impurity C	NMT 2.0%
Total for test A and B	NMT 3.0%
Residual solvent
Meth anol	NMT 2000ppm
Eth yl acetate	NMT 2000ppm
Dio xane	NMT 200ppm
Tolu ene	NMT 300ppm
Triethy lamine	NMT 200ppm
DMSO	NMT 5000ppm
Assay	97.0% and 102.0%