China Factory Supply High Purity Docetaxel Powder for Anti-Tumor with Cheap Price, Find details about China Food Additive Docetaxel Powder, High Purity Docetaxel Powder from China Factory Supply High Purity Docetaxel Powder for Anti-Tumor with Cheap Price
Product Name: | Docetaxel |
Other Name | docetaxel anhydrous |
CAS No. | 114977-28-5 |
Grade: | Phamaceutical Grade |
MF: | C43H53NO14 |
MW: | 807.879 |
Melting Point | 186-192 °C (dec.) |
Boiling point: | 900.5±65.0 °C at 760 mmHg |
Flash point: | 498.4±34.3 °C |
Density | 1.4±0.1 g/cm3 |
Shelf Life | 3 years |
Appearance | White powder |
Brand Name: | Oriherb |
Form | Powder |
Place of Origin: | Shaanxi, China (Mainland) |
Packaging: | Bottle, Can, Drum, Plastic Contain |
Standard: | USP EP JP etc. |
Introduction: | Docetaxel Anhydrous is the anhydrous form of docetaxel, a semisynthetic side-chain analogue of paclitaxel with antineoplastic property. Docetaxel binds specifically to the beta-tubulin subunit of microtubules and thereby antagonizes the disassembly of the microtubule proteins. This results in the persistence of aberrant microtubule structures and results in cell-cycle arrest and subsequent cell death. Docetaxel was patented in 1986 and approved for medical use in 1995. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. |
1. Approved in treatment of breast cancer, non-small cell lung cancer, advanced stomach cancer, head and neck cancer and metastatic prostate cancer.
2. Also being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers, soft tissue sarcoma and melanoma.
Docetaxel is given intravenously. Doses range from 60 mg/m2 to 100 mg/m2 every 3 weeks in combination with other chemotherapy agents. Dexamethasone also is administered prior to docetaxel to reduce the severity of fluid retention and occurrence of hypersensitivity reactions.
Related Products
Product Name | CAS No. | Purity |
Paclitaxel (GMP,DMF) | 33069-62-4 | 98% |
Docetaxel | 114977-28-5 | 99% |
Docetaxel Trihydrate | 148408-66-5 | 99% |
Cabazitaxel | 183133-96-2 | 99% |
7,10-dimethoxy-Baccatin III | 183133-94-0 | 99% |
Cephalomannine | 71610-00-9 | 98% |
10-DAB | 32981-86-5 | 99% |
Baccatine III | 27548-93-2 | 99% |