Product Name: TafluprostSynonyms: 209860-87-7;TAFLUPROST;(5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid 1-methylethyl ester;15,15-DIFLUORO-9ALPHA,11ALPHA-DIHYDROXY-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER;AFP-168;Tafluprost5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-,1-methylethyl ester, (5Z)-;MK2452CAS: 209860-87-7MF: C25H34F2O5MW: 452.53Boiling point: 552.9±50.0 °CDescription:Glaucoma is second only to cataracts as a causative factor of blindness. By 2010, it is estimated that approximately 60 million people worldwide will be afflicted by glaucoma, so effective treatments should garner a large market. PG analogs have been widely used for lowering IOP by increasing uveoscleral outflow through agonism of the prostanoid FP receptor, and currently marketed versions include latanoprost, unoprostone isopropyl ester, bimatoprost, and travoprost. Compared to the carboxylic acid of latanaprost (Ki=4.7 nM), the carboxylic acid of tafluprost displayed a 10-fold greater affinity for the prostanoid FP receptor (Ki=0.4 nM). The synthesis of tafluprost begins with a Wittig condensation of the protected bicyclic lactone carbaldehyde with a dimethyl phosphonate ketone derivative. ![Pharmaceutical Tafluprost Intermediate CAS 209860-87-7 for Treating Eyes](//image.made-in-china.com/226f3j00njQRtJaCAAbh/Pharmaceutical-Tafluprost-Intermediate-CAS-209860-87-7-for-Treating-Eyes.webp)
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Q1: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.Q2: What certificates and documents do you offer?A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.Q3: Why should I choose you?A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.Strict quality control-comes form our sophisticated management system.Professional and warm sales team-since we believe we can only win via our hard work in a competitive worldQuick response and excellent presale and after sale service-since we believe our customers deserve all the best service.