Genipin is the active compound found in the fruit of Gardenia jasminoides Ellis extract used as Chinese traditional medicine to relieve the symptoms of type 2 diabetes.

Genipin is an excellent natural cross-linker for proteins, collagen, gelatin, and chitosan cross-linking. It has low acute toxicity; much less toxic than glutaraldehyde and many other commonly used synthetic cross-linking reagents. It is also used for pharmaceutical purposes, such as choleretic action for liver disease control.

Furthermore, genipin can be used as a cross-linking agent for immobilized enzymes, as a regulating agent for drug delivery, as the raw material for gardenia blue pigment preparation, and as the intermediate for alkaloid syntheses.

Besides the medicinal usage, Genipin has also been a wide range of applications in other areas, such as react with an amino acid be Gardenia Blue which can be widely used in the food, printing, and dyeing industry; used as a biological fingerprint capture reagents; or natural cross-linking agent for enzyme immobilization and preparation of gel capsules as well as for medicinal uses.

1. Genipin is an excellent natural cross-linking agent.

2. Gardenia Extract may treat liver diseases.

3. It may treat gallbladder diseases by increasing bile flow but reducing the level of bile acid.

4. It may improve digestive function.

5. It may have a sedative effect and improve sleep.

6. Gardenia Extract Genipin may help reduce blood pressure.