Name  :   L-Citrulline
Shape :   White Powder

While citrulline is still an amino acid, it is not embedded in proteins in protein biosynthesis because it is not encoded for DNA, but some proteins still contain citrulline.These citrulline are produced by the peptide arginine iminase (PAD), which converts arginine to citrulline during the melons' ammonification process.Common proteins containing citrulline include human brain myelin basic protein (MBP), polykeratin microfilaments, and some histones.For example, cellulose and vimentin can be ammonified by melon from cell death and tissue inflammation.

                Citrulline is an α-amino acid, C6H13N3O3, which is produced from ornithine and amino formyl phosphate in the urea cycle or as a by-product of the production of NO by arginine catalyzed by nitric oxide synthase (NOS).

                 Patients with rheumatoid arthritis (about 80%) develop an immune response against the citrulline-carrying protein.Although the cause of this reaction mechanism is unknown, detecting antibodies can help in the diagnosis of such diseases.