High Purity 99% API CAS 54910-89-3 Fluoxetine Hydrochloride for Anti -Depression

Fluoxetine hydrochloride discovery of fluoxetine began at Eli Lilly in 1970 as a collaboration between Bryan Molloy and Robert Rathbun. Testing the physiological effects of these compounds in mice resulted in nisoxetine, a selective norepinephrine reuptake inhibitor currently widely used in biochemical experiments. This test which carried out by Jong-Sir Horng in May 1972, showed the compound later named fluoxetine to be the most strong and selective inhibitor of serotonin reuptake of the series. Two years later they had to issue a correction, admitting that the first SSRI was zimelidine developed by Arvid Carlsson and colleagues. In 1986, Fluoxetine made its appearance on the Belgian market and was approved for use by the FDA in the United States in December 1987. Fluoxetine was the fourth SSRI to make it to market, after zimelidine, indalpine and fluvoxamine. 

Medical uses:

Fluoxetine 20mg blister pack
Fluoxetine is frequently used to treat major depressive disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), bulimia nervosa, panic disorder, premenstrual dysphoric disorder, and trichotillomania.It has also been used for cataplexy, obesity, and alcohol dependence,as well as binge eating disorder.It has also been tried as a treatment for autism spectrum disorders with moderate success in adults.

Obsessive-compulsive disorder:

The efficacy of fluoxetine in the treatment of obsessive-compulsive disorder (OCD) was demonstrated in two randomized multicenter phase III clinical trials. The pooled results of these trials demonstrated that 47% of completers treated with the highest dose were "much improved" or "very much improved" after 13 weeks of treatment, compared to 11% in the placebo arm of the trial.The American Academy of Child and Adolescent Psychiatry state that SSRIs, including fluoxetine, should be used as first-line therapy in children, along with cognitive behavioral therapy (CBT), for the treatment of moderate to severe OCD.

Panic disorder:

The efficacy of fluoxetine in the treatment of panic disorder was demonstrated in two 12-week randomized multicenter phase III clinical trials that enrolled patients diagnosed with panic disorder, with or without agoraphobia. In the first trial, 42% of subjects in the fluoxetine-treated arm were free of panic attacks at the end of the study, vs. 28% in the placebo arm. In the second trial, 62% of fluoxetine treated patients were free of panic attacks at the end of the study, vs. 44% in the placebo arm.

Bulimia nervosa:

A 2011 systematic review of seven trials which compared fluoxetine to a placebo in the treatment of bulimia nervosa; six of which found a statistically significant reduction in symptoms such as vomiting and binge eating.However, no difference was observed between treatment arms when fluoxetine and psychotherapy were compared to psychotherapy alone.

COA

Company Profile

Guangzhou Biocar Pharmacy Co., Ltd., formerly known as Guangdong Yangye Pharmaceutical Factory established in 2005, is affiliated to Wuhan Biocar Group. With the rise of Internet +, company's business process is accelerating. The company's board of directors has decided to establish Guangzhou Yangye Biotechnology Co., Ltd. At the end of 2016. We have established close and stable cooperative relationship with over 420 manufacturers with long-term with consistent suppliers at India and China. Now the company has formed into a comprehensive chemical enterprise integrating scientific research, development, production, sales and service under all staffs' endless efforts. 
 

Guangzhou Biocar Pharmacy Co., Ltd. is located near Zhujiang New Town, Tianhe District, one of the prosperous areas in Guangzhou. This helps facilitate business negotiations at home and abroad. It is a high-tech enterprise centered in Guangdong, radiating across our country and facing the world. And it is mainly engaged in the research, development and sales of new chemical raw materials, the custom synthesis and import and export of pharmaceutical intermediates and APIs, the agency sales of pharmaceutical chemicals, the research and development, production and sales of flavors, fragrances and chemical raw materials. Its factory covers an area of more than 4, 000 acres and has more than 600 employees. It has always adhered to the tenet of "Being faithful, cultivating harmony and achieving win-win cooperation" and treats every customer sincerely.

We are looking forward to cooperating with you sincerely, and making mutual benefit and brilliance!

Our Service

 1.Cooperate with research institutions, we strictly control the process from raw material to finished product.

 2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.

 3.We can send the goods to your delivery address directly. It is relatively safe and fast. 

 4.Quick and clear response to customers questions.

 5.We could make our price discount if you place a substantial order with us.

 6.Products can be packaged according to customer requirements.

 

Packaging & Shipping