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Acetylcholinesterase Inhibitor Donepezil for Dementia Treatment 120014-06-4

China Acetylcholinesterase Inhibitor Donepezil for Dementia Treatment 120014-06-4, Find details about China Donepezil, 120014-06-4 from Acetylcholinesterase Inhibitor Donepezil for Dementia Treatment 120014-06-4

Model NO.
120014-06-4
Shelf Life
Two Years
Trademark
Chenxun
Transport Package
25kg / Drum
Specification
25Kg/ drum
Origin
China
HS Code
2933399090
Model NO.
120014-06-4
Shelf Life
Two Years
Trademark
Chenxun
Transport Package
25kg / Drum
Specification
25Kg/ drum
Origin
China
HS Code
2933399090
Acetylcholinesterase Inhibitor  Donepezil  for Dementia Treatment 120014-06-4
 
Product Description
 

Product Name:DONEPEZIL HYDROCHLORIDE

Synonyms:AKOS 226-31;E-2020;DONEPEZIL HCL;ARICEPT;DonepezilHcl120011-70-3/;DONEPEZIL (DONEPEZIL HYDROCHLORIDE);2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one hydrochloride;Donepezil hydrochloride

CAS:110119-84-1

MF:C24H30ClNO3

MW:415.95

 

Description

 

Donepezil is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the palliative treatment of Alzheimer's disease. Common side effects include gastrointestinal upset. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a biological half-life of about 70 hours, it can be taken once a day.

Donepezil has been tested in other cognitive disorders (and is sometimes used off label) including Lewy body dementia and vascular dementia, but it is not currently approved for these indications. Donepezil has been found to improve sleep apnea in Alzheimer's patients. Donepezil has also been studied in patients with Mild Cognitive Impairment, schizophrenia, attention deficit disorder, post-coronary bypass cognitive impairment, cognitive impairment associated with multiple sclerosis, CADASIL, and Down syndrome.

 

COA

 

TEST ITEMSPECIFICATIONRESULT
AppearanceOff white to white crystalline powderComplies
Solubilityfreely Freely soluble in chloroform, soluble
in water and Acetic acid, slightly soluble in
Acetonitrile and ethanol, insoluble in
Ethylacetoacetate and n-hexane		Complies
Identification(1)By IR absorption ,To match with working
standard		Complies
(2) The retention time of the major peak of
the sample should accord with that of the
working standard.		Complies
(3) Test for chlorides. Reponds to the test
for Chlorides.		Complies
PH4.0-7.06.10
Residue on ignition≤0.1%0.03%
Related substanceAny Unkonwn single impurity≤0.3%
Total ≤0.5%		0.04%
0.18%
Heavy metal≤10ppm<10ppm
Residual SolventsMethanol≤0.3%
Ethanol≤0.5%
Ethyl acetate≤0.5%
Toluene≤0.089%
Acetic acid≤0.5%		Not detected
Not detected
Not detected
Not detected
Not detected
Loss on drying≤0.5%0.20%
AssayOn dried base, C24H29NO3·HCl
should be 98.0% to 102.0%		100.20%
Conclusion: The product complies to Enterprise standard

Product Uses
 
UsageA nootropic. An inhibitor of acetylcholinesterase
UsageA labelled nootropic. An inhibitor of acetylcholinesterase.
UsageAntialzheimer
UsageLabeled Donepezil, intended for use as an internal standard for the quantification of Donepezilby GC- or LC-mass spectrometry.
DefinitionChEBI: Donepezil hydrochloride is a centrally acting reversible acetyl cholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's
disease where it is used to increase cortical acetylcholine.
 

Acetylcholinesterase Inhibitor Donepezil for Dementia Treatment 120014-06-4

Packing

· 1kg/aluminium foil bag, with two plastic bags inside.
· 25kg/fiber drum, with two plastic bags inside.
Size:ID 42cm*H52cm,0.08m3/drum;
Net Weight:25kgs Gross Weight:28kgs.
Acetylcholinesterase Inhibitor Donepezil for Dementia Treatment 120014-06-4

SHIPPING ADVISE

 By Express
Sultable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to plck up the goods.
 By Air
Sultable for more than 50 kg, Fast: 4-5 days, HIgh cost, alrport to alrportprofesslonal broker needed.
 By sea
Sultable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, protesslonal broker needed.


FAQ

Q1: Can i get small sample?
A: Yes, FREE SAMPLES of some products can be sent on request, but the shipping cost be paid by our customers.
Q2. How to confirm the products quality before placing orders?
A: COA first for you to check the specification,and we test every batch of our product
by HPLC.UV,GC AND TLC AND etc. We also cooperate with independent third party
lab such as SGS,PONY etc.  

Q3: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Money Gram. Also L/C at sight is acceptable for large amount

Why Choose Us
  1. We have 10 years of experience in exporting products, strong market response capabilities and a wide range of trading partners.
  2. We have a variety of certified factories to produce high quality products.
  3. We offer full link hosted services from production to delivery.
  4. We provide testing services prior to shipment of the product.
  5. We will cultivate customers in every country market, let customers develop quickly with us, and win-win cooperation.
  6. Stable supply, delivery on time, quality assurance.

 

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