1,Inhibition of angiotensin converting enzyme (ACE) activity

ACE is a key enzyme in the renin-angiotensin system. Its physiological function is to convert angiotensin into angiotensin. Angiotensin binds to its receptors and can cause vasoconstriction and increase blood pressure.Inhibition of ACE activity, can reduce the production of angiotensin, has the effect of lowering blood pressure.Inhibition of ACE activity has become the target of antihypertensive drugs.

2. Antitumor activity

Some peptides with small molecular weights (600 ~ 1000Da) were isolated from the chromatin of wheat germ. It was found that these peptides could significantly inhibit the growth of HeLa cancer cells in a dose-dependent way.The hydrolytic product of wheat protein also contains the component of Eucalyptus japonicus, which is a long peptide containing 43 amino acids. This long peptide has a good anti-cancer effect. The mechanism of this peptide is related to its inhibition of nuclear histone acetylase activity.

3. Agglutination and anticoagulant activity

Some scholars found that the hydrolysate of wheat gladin could induce the agglutination reaction of K562 cells, while wheat gladin itself did not. After the separation and purification of the hydrolysate, two peptides were identified to participate in the agglutination reaction, whose sequences were Leu-Gly-Gly-Gln-Gl-Pro-Phe-Pro-Pro-Gln-Pro-Tyr and Pro-Gly-Pro-Gl-Pro-Phe-Pro-Ser-Gln-Pro-Tyr, respectively.When the six amino acids at the carboxyl terminus of the former and the five amino acids at the amino terminus of the latter are knocked out, they can still exhibit their agglutination activity.

4. Antioxidant activity