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Pharmaceutical Intermediate Raw Powder Agomelatine / S20098 CAS 138112-76-2 For Anti-Depression

Quick Details:

Chemical name: Agomelatine
CAS registry number: 138112-76-2

Chemical Formula: C15-H17-N-O2
Molecular Weight: 243
Therapeutic Category: Antidepressant: Melatonin receptor agonist
Chemical Names: N-[2-(7-metoxy-1-naphtyl)etyl]acetamide (WHO),N-[2-(7-Metoxynaphtalen-1-yl)etyl]acetamide (BAN)
Appearance: White powder
Drug class: Atypical antidepressant drug

What is Agomelatine?
Do you think agomelatine is a solid antidepressant? How do you think it compares to other more typical antidepressants like Prozac?

Agomelatine's unique pharmacology and favorable side effect profile make it a boon for depressed patients, especially those who have not responded to conventional antidepressants.

Application:

Valdoxan tablets contain the active ingredient agomelatine, which is a type of medicine called an antidepr

essant. It is used to treat depression.

Agomelatine acts on the melatonin and serotonin receptors in the brain.

Melatonin is a hormone made by the pineal gland, a structure in the brain. It is normally released soon after it starts to get dark. The amount produced then increases until about four am, before dropping off again. Melatonin is linked with the control of circadian rhythms and promoting sleep. It works by acting on melatonin receptors in the brain.

Agomelatine mimics the action of melatonin and helps to re-synchronise the body's circadian rhythms. These include mood, anxiety, appetite, body temperature and sleep/wake cycles. These circadian rhythms, particularly sleep cycles, are severely disturbed in people with depression. Agomelatine's main action is to improve the onset and quality of sleep and this in turn has an antidepressant effect.

Agomelatine also helps to improve mood in depression by increasing noradrenaline and dopamine release in the brain. These are natural chemicals called neurotransmitters that are involved, amongst other things, in regulating mood.

Usage:

Agomelatine is indicated for the treatment of major depressive episodes in adults.Ten placebo controlled trials have been performed to investigate the short term efficacy of agomelatine in major depressive disorder. At the end of treatment, significant efficacy was demonstrated in six of the ten short-term double-blind placebo-controlled studies.Two were considered "failed" trials, as comparators of established efficacy failed to differentiate from placebo. Efficacy was also observed in more severely depressed patients in all positive placebo-controlled studies.The maintenance of antidepressant efficacy was demonstrated in a relapse prevention study.

Related Products:
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 
3. How to cooperate with us?
You can contact us for cooperation through the website contact information, or contact with the salesmen in our company. We will connect you about the specific detail via email. 

Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.





Packaging Details

1.25kg packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside.Or according customer requairments.

2.Delivery Time:whith 3-5 working days after get the payment.

3.Shipping:We have professional shipping afent,based on customers'requairments for transport.

4.By express: Fedex, DHL, EMS,UPS etc.   By sea and By air





Payment terms: TT,Bitcoin,Western union , Money gram or Bank transfer
Delivery: 1-3 working days after payment confirmed
Shipping: Door to door safe deliver by air,by sea,express including EMS,DHL,UPS,TNT,FedEX
Packaging Details: Safe package or as required
Discount: Large quantity ordered
 

Package and shipping:

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Packaging Details:25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside

Delivery Detail: within 3 days when get the payment.

Shipping :

We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR