China Supplier Leading Supplier Pemetrexed Disodium Heptahydrate CAS No 357166-29-1
China Supplier Leading Supplier Pemetrexed Disodium Heptahydrate CAS No 357166-29-1, Find details about China Pemetrexed, Anti-Cancer Intermediate from China Supplier Leading Supplier Pemetrexed Disodium Heptahydrate CAS No 357166-29-1
Basic Info.
Model NO.
PX-A
CAS
52-24-4
Sample
Free
Usage
API
Product Nane
Pemetrexed
Colour
White
Appearance
White Powder
Supply
Bulk
Trademark
OEM
Transport Package
25kg/Drum
Specification
25KG/Bag
Origin
China
HS Code
3001200010
Model NO.
PX-A
CAS
52-24-4
Sample
Free
Usage
API
Product Nane
Pemetrexed
Colour
White
Appearance
White Powder
Supply
Bulk
Trademark
OEM
Transport Package
25kg/Drum
Specification
25KG/Bag
Origin
China
HS Code
3001200010
Product Desciption
China Supplier Leading Supplier Pemetrexed Disodium Heptahydrate CAS No 357166-29-1
Product Name | Pemetrexed disodium hemipenta hydrate |
Appearance | White or off- white powder |
Assay | 99%min, 98.0% --101.0% |
Test | HPLC |
Certificate | ISO 9001 |
CAS | 357166-30-4 |
| MF | 2(C20H19N5Na2O6).5(H2O) |
| Storage Temperature | Cool Dry Place |
Despcription
Pemetrexed disodium heptahydrate is an organic sodium salt that is the heptahydrate form of pemetrexed disodium. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). It has a role as an antimetabolite, an antineoplastic agent, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, an EC 2.1.1.45 (thymidylate synthase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor. It is an organic sodium salt and a hydrate. It contains a pemetrexed disodium.Function
Malignant pleural mesotheliomaPemetrexed Krka in combination with cisplatin is indicated for the treatment of chemotherapy naïve patients with unresectable malignant pleural mesothelioma.Non-small cell lung cancerPemetrexed Krka in combination with cisplatin is indicated for the first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology.Pemetrexed Krka is indicated as monotherapy for the maintenance treatment of locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology in patients whose disease has not progressed immediately following platinum-based chemotherapy.Pemetrexed Krka is indicated as monotherapy for the second-line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology.
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