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Raw Pharmaceutical Grade Material Sirolimus CAS 53123 -88-9 Powder Rapamycin

China Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin, Find details about China Rapamycin, Rapamycin Chemical from Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin

Model NO.
HRK-Rapamycin
Product Name
Rapamycin Powder
Appearance
White Crystalline Powder
Test
HPLC
Mf
C51h79no13
CAS
53123-88-9
MW
914.18
Active Ingredient
Rapamycin
Sample
Rapamycin Avaliable
Certificate
GMP ISO USP Bp
Assay
90% Min
Grade Standard
Feed Grade, Food Grade, Medicine Grade
Application
Vertinary Raw Materials
Type of Product
Auxiliaries and Other Medicinal Chemicals
Storage
Cool Dry Place
Shelf Life
2 Years Proper Storage
Trademark
Henrikang
Transport Package
1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
Specification
99% min Rapamycin
Origin
Shaanxi China
Model NO.
HRK-Rapamycin
Product Name
Rapamycin Powder
Appearance
White Crystalline Powder
Test
HPLC
Mf
C51h79no13
CAS
53123-88-9
MW
914.18
Active Ingredient
Rapamycin
Sample
Rapamycin Avaliable
Certificate
GMP ISO USP Bp
Assay
90% Min
Grade Standard
Feed Grade, Food Grade, Medicine Grade
Application
Vertinary Raw Materials
Type of Product
Auxiliaries and Other Medicinal Chemicals
Storage
Cool Dry Place
Shelf Life
2 Years Proper Storage
Trademark
Henrikang
Transport Package
1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
Specification
99% min Rapamycin
Origin
Shaanxi China
                   Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin
                             Raw Pharmaceutical Grade Material Sirolimus  CAS 53123-88-9 Powder Rapamycin
 
Product NameRaw Pharmaceutical Grade Material Sirolimus  CAS 53123-88-9 Powder Rapamycin
CAS53123-88-9
AppearanceWhite Crystalline Powder
Molecular formulaC51H79NO13
Molecular Weight914.18
Assay98%
Shelf Life24 months when properly stored
StorageKeep in a cool, dry, dark location
 
Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin
What is Rapamycin?
 
Rapamycin is a member of the macrolide immunosuppressant family and a FRAP inhibitor. 
Rapamycin exhibits binding and inhibitory actions to the FK506 binding protein (FKBP5) proline rotamase via simultaneous binding by FKBP12 and FRAP. FRAP (RAFT1) proteins exhibit homology to PI 4- and PI 3-kinases,which have PI 4-kinase and autophosphorylating activities.
The rapamycin/FKBP complex does not inhibit the FRAP PI 4-kinase activity,but does inhibit FRAP autophosphorylation. 
Rapamycin is unique in its ability to inhibit lymphokine induced cell proliferation at the G1 and S phase as well as an irreversible cellular arrest at the G1 phase in S. cerevisiae cells. 
Rapamycin also exhibits selective signal blocking leading to the activation of p70/85 S6 kinase, which is
potentially due to the inhibition of FRAP autophosphorylation or protein kinase activity. Angiogenesis inhibition is also exhibited,possibly through the inhibition of the Akt pathway. 
Rapamycin is an inhibitor of mTOR.
 
 

Function And Application of Rapamycin

Rapamycin is a triene macrolide antibiotic,which demonstrates anti-fungal,anti-inflammatory,anti-tumor and immunosuppressive
properties.
Rapamycin has been shown to block T-cell activation and proliferation,as well as,the activation of p70 S6 kinase and exhibits strong
binding to FK506 binding proteins. 
Rapamycin also inhibits the activity of the protein,mTOR(mammalian target of rapamycin) which functions in a signaling pathway to
promote tumor growth.

Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction
of mTOR with target proteins in this signaling pathway.
 
Rapamycin (RAPA) is a novel macrolide immunosuppressant is now often used as a transplanted organ to maintain immunity drugs
(especially kidney transplants), to mitigate the immune organ rejection after transplant surgery, but scientists it recently found another
purpose: for the treatment of Alzheimer's disease (senile dementia).

Target of rapamycin (mTOR) as an intracellular kinases pathway abnormalities can induce a variety of diseases. As rapamycin mTOR
inhibitor targeting, to treat with this pathway is closely related to tumors, including renal cell carcinoma, lymphoma, lung cancer,
liver cancer, breast cancer, neuroendocrine carcinoma and gastric cancer
 
Product NameCAS No.Product NameCAS No.
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Nitenpyram120738-89-8Praziquantel/Biltricide55268-74-1
Fenbendazole43210-67-9Tetramisole Hcl5086-74-8
Levamisole14769-73-4Ponazuril9004-4-2
Diclazuril101831-37-2Florfenicol73231-34-2
Ivermectin70288-86-7Enrofloxacin Hcl112732-17-9
Albendazole54965-21-8Mebendazole31431-39-7

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Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin
Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin


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Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin

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Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin

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Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin

Packaging & Logistics

Package:

1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.
 

2. Shipping Advise: 

1. By Express

------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.

2. By Air 

------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.

Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin

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Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin
Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin
 

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