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5- Aza -2-Deoxycytidine CAS 2353-33-5 Decitabine for Myelodysplastic Syndrome

China 5-Aza-2-Deoxycytidine CAS 2353-33-5 Decitabine for Myelodysplastic Syndrome, Find details about China 2353-33-5, Decitabine from 5-Aza-2-Deoxycytidine CAS 2353-33-5 Decitabine for Myelodysplastic Syndrome

Model NO.
2353-33-5
Shelf Life
Two Years
Trademark
Chenxun
Transport Package
25kg / Drum
Specification
25Kg/ drum
Origin
China
HS Code
934999091
Model NO.
2353-33-5
Shelf Life
Two Years
Trademark
Chenxun
Transport Package
25kg / Drum
Specification
25Kg/ drum
Origin
China
HS Code
934999091
5-Aza-2-deoxycytidine CAS 2353-33-5 Decitabine for Myelodysplastic Syndrome
 
Basic Info
Product Name:5-Aza-2'-deoxycytidine
Synonyms:4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one;5-Aza-2'-deoxycytidine,98+%;4-Amino-1-(2-deoxy-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one;Decitabine(NSC127716);4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-on;4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-one;5-azadeoxycytidine;5-triazin-2(1h)-one,4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-3
CAS:2353-33-5
MF:C8H12N4O4
MW:228.21
EINECS:219-089-4

 

Properties 

 

Melting point~200 °C (dec.)
alphaD22 +68.5° (30 min) +57.8° (6 hr) (c = 0.5 in water)
Boiling point370.01°C (rough estimate)
density1.3771 (rough estimate)
refractive index1.6590 (estimate)
storage temp.−20°C
solubilityacetic acid/water (1:1): 50 mg/mL
pka14.02±0.60(Predicted)
formPowder
colorWhite to Off-white


Application 

 

Used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines.

Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively

COA
 

Items TestedSpecificationResult
CharactersWhite to off-white crystalline powderConfirms
Melting Point198-203 Degree Confirms
Assay (HPLC)≥99.00% 99.51%
Loss on DryingNot more than1.0%0.21%
Related substancesNot more than 1.0%0.11%
The largest impurities≤0.3%0.09%
Total impurities(HPLC)≤1.0%0.43%
Total aerobic microbial≤100cfu/g59cfu/g
Heavy Metal≤10ppmconforms
Staphylococcus aureusAbsenceAbsence
Pseudomonas aeruginosaAbsenceAbsence
Salmonella speciesAbsenceAbsence
EscherichiaAbsenceAbsence
 


5-Aza-2-Deoxycytidine CAS 2353-33-5 Decitabine for Myelodysplastic Syndrome

Packing

· 1kg/aluminium foil bag, with two plastic bags inside.
· 25kg/fiber drum, with two plastic bags inside.
Size:ID 42cm*H52cm,0.08m3/drum;
Net Weight:25kgs Gross Weight:28kgs.
5-Aza-2-Deoxycytidine CAS 2353-33-5 Decitabine for Myelodysplastic Syndrome

SHIPPING ADVISE

 By Express
Sultable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to plck up the goods.
 By Air
Sultable for more than 50 kg, Fast: 4-5 days, HIgh cost, alrport to alrportprofesslonal broker needed.
 By sea
Sultable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, protesslonal broker needed.


FAQ

Q1: Can i get small sample?
A: Yes, FREE SAMPLES of some products can be sent on request, but the shipping cost be paid by our customers.
Q2. How to confirm the products quality before placing orders?
A: COA first for you to check the specification,and we test every batch of our product
by HPLC.UV,GC AND TLC AND etc. We also cooperate with independent third party
lab such as SGS,PONY etc.  

Q3: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Money Gram. Also L/C at sight is acceptable for large amount

Why Choose Us
  1. We have 10 years of experience in exporting products, strong market response capabilities and a wide range of trading partners.
  2. We have a variety of certified factories to produce high quality products.
  3. We offer full link hosted services from production to delivery.
  4. We provide testing services prior to shipment of the product.
  5. We will cultivate customers in every country market, let customers develop quickly with us, and win-win cooperation.
  6. Stable supply, delivery on time, quality assurance.

 

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