China Medicine Grade 99% Cromoglycate Sodium Cromoglycate Powder, Find details about China Powder Sodium, Material Sodium from Medicine Grade 99% Cromoglycate Sodium Cromoglycate Powder
Product name:Sodium Cromoglycate
Cas: 15826-37-6
EINECS: 240-279-8
Appearance : white powder
Molecular weight : 468.37
Molecular formula: C23H14Na2O11
Density: 1.623
Mp: 241-242°C
Air & Water Reactions : Water soluble.
Synonyms:disodium cromoglicate; Disodium 5,5-[(2-hydroxytrimethylene)-bis-(oxy)]-bis[4-oxo--1-benzopyran-2; Sodium Cromoglicate; CROMOGLICATE SODIUM; Disodium
Cromoglycate acid (INN) (also referred to as cromolyn (USAN), cromoglycate(former BAN), or cromoglicate) is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release ofinflammatory chemicals such as histamine from mast cells.
Cromolyn sodium has been used to treat for asthma for many years. It is a derivative of khellin and is proved to be a unique antiallergic agent. The prior administration of cromolyn sodium inhibits allergen-induced histamine release in the animal experiments. Because the oral absorption of cromolyn sodium is minimal and only the powder form of it is available, cromolyn sodium is usually used through being inhaled from a special apparatus. Cromolyn sodium can suppress both immediate and late-onset asthmatic responses and suppress the release of NCF-A. It also inhibits the impairment of mucociliary transport induced by specific bronchial challenge. Moreover, cromolyn sodium also ameliorates exercise-induced asthma
Application
1. As a nasal spray to treat allergic rhinitis. 2. In a nebulizer solution for aerosol administration to treat asthma. 3. As an inhaler (Intal) for preventive management of asthma. 4. As eye drops for allergic conjunctivitis 5. In an oral form (Gastrocrom) to treat mastocytosis, dermatographic urticaria andulcerative colitis. Another oral product, Intercron (sodium cromoglicate in distilled water, from Zambon France), is used for food allergies. |
1) And sensitive mast cell membrane outside of the calcium channel, preventing calcium influx, inhibition of mast cell degranulation, reducing the release of histamine, slow reactant, leukotrienes and other inflammatory mediators, the role ofspecies selectivity and organ most sensitive to human lung mast cells.
2) Inhibition of sensory nerve endings to release substance P, neurokinin A and B induced tracheal smooth muscle spasm and mucosal edema.
3) Reducing the sensitivity of people with asthma for non-specific stimuli, reducing the attack of bronchospasm.
25kgs/Fiber drum outside and plastic bag inside; 1-25kgs packaging, aluminium Foil bag outside and double plastic bag inside; Delivery Detail: within 3 days when get the payment Shipping: We have Professional shipping agent, based on customers ' demand for transport By express: FEDEX,DHL,EMS ,UPS,TNT ect. By SEA and By AIR |
24 hours online 1.Any inquiries will be replied with in 12 hours. 2.Dedication to quatity,supply& service. 3.Strictly on selecting raw meterials. 4.Reasonable & competitive price ,fast lead time. 5.Smple order in stock and one week for bulk production. 6. We have strong cooperation with FEDEX,TNT,DHL,EMS,or you also can choose your own shipping agent.. |