Product name:Sodium Cromoglycate

Cas: 15826-37-6

EINECS: 240-279-8

Appearance : white powder

Molecular weight : 468.37

Molecular formula: C23H14Na2O11

Density: 1.623

Mp: 241-242°C

Air & Water Reactions : Water soluble.
 

Synonyms:disodium cromoglicate; Disodium 5,5-[(2-hydroxytrimethylene)-bis-(oxy)]-bis[4-oxo--1-benzopyran-2; Sodium Cromoglicate; CROMOGLICATE SODIUM; Disodium

Cromoglycate acid (INN) (also referred to as cromolyn (USAN), cromoglycate(former BAN), or cromoglicate) is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release ofinflammatory chemicals such as histamine from mast cells.

Cromolyn sodium has been used to treat for asthma for many years. It is a derivative of khellin and is proved to be a unique antiallergic agent. The prior administration of cromolyn sodium inhibits allergen-induced histamine release in the animal experiments. Because the oral absorption of cromolyn sodium is minimal and only the powder form of it is available, cromolyn sodium is usually used through being inhaled from a special apparatus. Cromolyn sodium can suppress both immediate and late-onset asthmatic responses and suppress the release of NCF-A. It also inhibits the impairment of mucociliary transport induced by specific bronchial challenge. Moreover, cromolyn sodium also ameliorates exercise-induced asthma