Antimicrobial Powder Rapamycin Spiramycin Adipate

China Antimicrobial Powder Rapamycin Spiramycin Adipate, Find details about China Spiramycin, Spiramycin Adipate from Antimicrobial Powder Rapamycin Spiramycin Adipate

Model NO.
Spiramycin
Name
Spiramycin
Mf
C43h74n2o14
CAS
8025-81-8
Trademark
HS
Transport Package
Drum
Specification
99%
Origin
China
HS Code
2904201000
Model NO.
Spiramycin
Name
Spiramycin
Mf
C43h74n2o14
CAS
8025-81-8
Trademark
HS
Transport Package
Drum
Specification
99%
Origin
China
HS Code
2904201000
Antimicrobial Powder Rapamycin Spiramycin Adipate
English namespiramycin 
Molecular FormulaC43H74N2O14
Molecular Weight843.0527
CAS Registry Number8025-81-8
EINECS232-429-6
QualityBP/EP/USP
Density1.21g/cm3
Boiling point913.7°C at 760 mmHg
Refractive index1.549
Flash point506.4°C
Vapour Pressur0mmHg at 25°C
AppearanceWhite to off white powder.
Applicationantibiotic medicines for staphylococcus, s. pyogenes, 
streptococcus pneumoniae, syphilis helicoid etc infection.

What is spiramycin?

Spiramycin, white or slightly yellow powder, slightly odor; Micro-hygroscopic;

This product is dissolved in methanol, ethanol, acetone or ether, almost insoluble in water, insoluble in petroleum ether.

It is a macrolide antibiotic obtained from the broth of Streptomyces ambofaciens.

Spiramycin is acetate acetate of acetylspiramycin, which shows strong antibacterial effect after oral administration of deacetylation. Spiramycin is a very strong bacteriostatic agent that only acts as a bactericidal agent at very high concentrations.
 

Introduction

Spiramycin is a macrolide antibiotic. It is used to treat toxoplasmosis and various other infections of soft tissues. Although used in Europe, Canada and Mexico, spiramycin is still considered an experimental drug in the United States, but can sometimes be obtained by special permission from the FDA for toxoplasmosis in the first trimester of pregnancy.

Antimicrobial Powder Rapamycin Spiramycin Adipate

What function & Application does spiramycin have?

 has a strong antibacterial effect in vivo and post-antibacterial effect (PAE), can enhance the phagocytosis of phagocytic cells, and is widely distributed in the body. This product is higher than the concentration of erythromycin in tissue cells, and the side effects are less than erythromycin. This product can be used to treat ear, nose, throat and respiratory tract infections caused by gram-positive bacteria and certain gram-negative bacteria. It is suitable for the treatment of otitis media, periodontitis, acute sinusitis and other oral and otolaryngitis caused by sensitive bacteria. Section infection. It can also be used to treat toxoplasmosis.

Antimicrobial Powder Rapamycin Spiramycin Adipate
 
Antimicrobial Powder Rapamycin Spiramycin Adipate
ItemsSpecificationsResults
AppearanceA white or slightly yellowish powderWhite powder
Identification Conform
A.  UV SpectrumThe specific absorbance at the maximum (232nm) is about 340.
B. TLCCorresponds to reference solution.
C. Color ReactionBrown colour.
pH8.5-10.59.6
Specific optical rotation-80°- -85°(dried substance)-83°
Composition (HPLC)Spiramycin≥80.0 %88.20%
Spiramycin≤5.0 %0.30%
Spiramycin≤10.0 %3.70%
Total Spiramycins ≥90.0 %92.20%
Related substances (HPLC)≤2.0 %Conform
Heavy metals≤20ppmConform
Loss on drying≤3.5 %1.40%
Sulphated ash≤0.1 %Conform
Assay (wet substance)No limits (IU/mg)4305 IU/mg
Assay (dried substance)≥4100 IU/mg4366 IU/mg
CONCLUSIONCONFORM TO EP VII
Antimicrobial Powder Rapamycin Spiramycin AdipateAntimicrobial Powder Rapamycin Spiramycin AdipateAntimicrobial Powder Rapamycin Spiramycin AdipateAntimicrobial Powder Rapamycin Spiramycin AdipateAntimicrobial Powder Rapamycin Spiramycin Adipate