High Purity Pharmaceutical Grade Imiquimod CAS 99011-02-6
China High Purity Pharmaceutical Grade Imiquimod CAS 99011-02-6, Find details about China 4-Amino- 1-Isobutyl-1h-Imidazo[4 5-C]Quinoline, Imiquimod from High Purity Pharmaceutical Grade Imiquimod CAS 99011-02-6
Basic Info.
Model NO.
Imiquimod
Trademark
xingjiu
Transport Package
Bag/Drum
Specification
99%
Origin
China
Model NO.
Imiquimod
Trademark
xingjiu
Transport Package
Bag/Drum
Specification
99%
Origin
China
Product Desciption
High Purity Pharmaceutical Grade Imiquimod CAS 99011-02-6
Imiquimod Basic information
Imiquimod Chemical Properties
Imiquimod Chemical Properties
White crystalline powder, melting at 166.5 ºC.
Imiquimod Uses
(1) It can be used for anti-genital warts and as immunomodulators
(2) immunomodulator
(3) raw material for Latamoxef, Cefminox, Ceftizoxime, Cefoxitin, Cefmetazole
(4) An immune response modifier. It stimulates the production of interferon-a
Imiquimod Description
Aldara was launched in the US for the topical treatment of genital warts caused by human papillomavirus (HPV). It can be prepared in a six step approach beginning with the nucleophilic substitution of 4-chloro-3-nitroquinolone with isobutylamine or via a thermal electrocyclic ring closure of 1 - and 2-azahexatriene systems. Aldara has antiviral and antitumor properties, with the former activity arising from the induction of cytokines, in particular, INF-α. Aldara also induces TNF-γ, IL-1α, IL-1β, IL-1ra, IL-6, IL-8, IL-10, GM-CSF, G-CSF and MID-la formation 1-4 hr after stimuli. The exact cells responsible for the response have not been determined, however, it is not activating T lymphocytes, NK cells, B lymphocytes, or dendritic stem cells but monocytes (CD14+, CD36+, HLA-DR+, HLA-DQ±, CD19-, CD16- and CD23-) are partly responsible. The speculation is that Aldara may interact with a kinase modulating the transduction pathway leading to cytokine genes. There is no direct antiviral activity (induction of IFN does not follow true dose response) and it is not mutagenic. The hydroxylated metabolite also induces IFN-α.
Our Factory
Packing and Shipping
1) 1 kg with double plastic container inside/Aluminum foil bag .
2) 1-5 kg,carton.
Shipped in 3 days after payment.
Payment Terms
Imiquimod Basic information
| Product Name: | Imiquimod |
| Synonyms: | R-837;S-26308;1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine, R-837, S-26308, Aldara;IMIQUIMOD /4-AMINO- 1-ISOBUTYL-1H-IMIDAZO[4,5-C]QUINOLINE;1-(2-methylpropyl)-1H-imidazo(4,5-quinolin-4-amine);1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINE;4-amino- 1-isobutyl-1h-imidazo[4,5-c]quinoline;IMIQUIMOD |
| CAS: | 99011-02-6 |
| MF: | C14H16N4 |
| MW: | 240.3 |
| EINECS: | 619-387-8 |
| Product Categories: | Furans ,Coumarins;Other APIs;Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;ALDARA |
Imiquimod Chemical Properties
| Melting point | 292-294°C |
| Boiling point | 456.7±48.0 °C(Predicted) |
| density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: soluble |
| form | White solid |
| pka | 6.28±0.30(Predicted) |
| Water Solubility | Soluble in dimethyl sulfoxide and dimethyl formamide. Slightly soluble in water. Insoluble in ethanol. |
| λmax | 245nm(H2O/MeOH)(lit.) |
| Merck | 14,4922 |
| Stability: | Incompatible with strong oxidizing agents. |
| InChIKey | DOUYETYNHWVLEO-UHFFFAOYSA-N |
| CAS DataBase Reference | 99011-02-6(CAS DataBase Reference) |
Imiquimod Chemical Properties
White crystalline powder, melting at 166.5 ºC.
Imiquimod Uses
(1) It can be used for anti-genital warts and as immunomodulators
(2) immunomodulator
(3) raw material for Latamoxef, Cefminox, Ceftizoxime, Cefoxitin, Cefmetazole
(4) An immune response modifier. It stimulates the production of interferon-a
Imiquimod Description
Aldara was launched in the US for the topical treatment of genital warts caused by human papillomavirus (HPV). It can be prepared in a six step approach beginning with the nucleophilic substitution of 4-chloro-3-nitroquinolone with isobutylamine or via a thermal electrocyclic ring closure of 1 - and 2-azahexatriene systems. Aldara has antiviral and antitumor properties, with the former activity arising from the induction of cytokines, in particular, INF-α. Aldara also induces TNF-γ, IL-1α, IL-1β, IL-1ra, IL-6, IL-8, IL-10, GM-CSF, G-CSF and MID-la formation 1-4 hr after stimuli. The exact cells responsible for the response have not been determined, however, it is not activating T lymphocytes, NK cells, B lymphocytes, or dendritic stem cells but monocytes (CD14+, CD36+, HLA-DR+, HLA-DQ±, CD19-, CD16- and CD23-) are partly responsible. The speculation is that Aldara may interact with a kinase modulating the transduction pathway leading to cytokine genes. There is no direct antiviral activity (induction of IFN does not follow true dose response) and it is not mutagenic. The hydroxylated metabolite also induces IFN-α.
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Our Factory
Xingtai Xingjiu New Material Technology Co., Ltd. was founded in 2018 and located in Xingtai City, Hebei Province.Our company aims to be a leading materials science company in innovation, customer orientation, inclusiveness and sustainability, committed to the sustainable development of society through our expertise in materials science and deep collaboration with our customers.
Xingjiu company products industrial intermediates, cosmetics raw materials, solvents and other daily chemical raw materials, to provide customers with a wide range of technology based differentiated products and right solutions.Our goal is to become a leading manufacturer of chemicals.With vigorous and progressive spirit and strong competitive strength, the company will strive to provide customers with high quality industrial products and excellent service, in order to achieve the lofty goals.
Xingjiu company adheres to the four core values of customer first, team building, innovation and responsibility to achieve the common development of the company and the society.If you are interested in our products, please send us emails or call us.We will get back to you in time.
Xingjiu company products industrial intermediates, cosmetics raw materials, solvents and other daily chemical raw materials, to provide customers with a wide range of technology based differentiated products and right solutions.Our goal is to become a leading manufacturer of chemicals.With vigorous and progressive spirit and strong competitive strength, the company will strive to provide customers with high quality industrial products and excellent service, in order to achieve the lofty goals.
Xingjiu company adheres to the four core values of customer first, team building, innovation and responsibility to achieve the common development of the company and the society.If you are interested in our products, please send us emails or call us.We will get back to you in time.
Packing and Shipping
1) 1 kg with double plastic container inside/Aluminum foil bag .
2) 1-5 kg,carton.
3) 25 kg with double plastic container inside/Fiber drum outside.
Or as your request.Shipped in 3 days after payment.
| Fast | Suitable | |
| DHL / FEDEX / EMS | 3-7 days | 50 kg |
| By Air | 5-15 days | > 50kg |
| By Sea | 10-45 days | > 1000kg |
Payment Terms
How To Proceed You Oreder:
1: Please let me know the items you are favorable, quantities, and the destination country.
2: You confirm all detail, and offer purchasing order.
3: We send the detail price of our product and offer the suitable shipping method for reference.
4: You confirm the order and pay mony 100% in advance and send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements.
5: We arrange the shipment according to your requirements, and tracking code will be offered after claiming the payment within 24h, then you can track your parcel at any moment.
6: We offer after-sales services after service after you receive your parcel.
Why Choose Us
1. the customer comes first, we provide reasonable price, high quality product and prompt shipment
2. We can send the goods to your delivery address directly. it is relatively safe and fast. We have ready goods in stock.
3. quick and clear response to customers questions.
warm after sale service, we will help to solve the problems in your wusge.
4. we could make our price discount if you place a substanial order with us.
1: Please let me know the items you are favorable, quantities, and the destination country.
2: You confirm all detail, and offer purchasing order.
3: We send the detail price of our product and offer the suitable shipping method for reference.
4: You confirm the order and pay mony 100% in advance and send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements.
5: We arrange the shipment according to your requirements, and tracking code will be offered after claiming the payment within 24h, then you can track your parcel at any moment.
6: We offer after-sales services after service after you receive your parcel.
Why Choose Us
1. the customer comes first, we provide reasonable price, high quality product and prompt shipment
2. We can send the goods to your delivery address directly. it is relatively safe and fast. We have ready goods in stock.
3. quick and clear response to customers questions.
warm after sale service, we will help to solve the problems in your wusge.
4. we could make our price discount if you place a substanial order with us.
FAQ
Q1. Can I have a sample order for your products?
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable.
Q2. What about the lead time?
A:Sample needs 3-5 days, mass production time needs 1-2 weeks for order quantity more than
Q3. Do you have any MOQ limit for order?
A: Low MOQ, 10-100g for sample checking is available
Q4. How do you ship the goods and how long does it take to arrive?
A: We usually ship by DHL, UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional.
Q5. How to proceed an order for your products?
A: Firstly let us know your requirements or application.
Secondly We quote according to your requirements or our suggestions.
Thirdly customer confirms the samples and places deposit for formal order.
Fourthly We arrange the production.
If you have any other needs, please contact me.
Q1. Can I have a sample order for your products?
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable.
Q2. What about the lead time?
A:Sample needs 3-5 days, mass production time needs 1-2 weeks for order quantity more than
Q3. Do you have any MOQ limit for order?
A: Low MOQ, 10-100g for sample checking is available
Q4. How do you ship the goods and how long does it take to arrive?
A: We usually ship by DHL, UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional.
Q5. How to proceed an order for your products?
A: Firstly let us know your requirements or application.
Secondly We quote according to your requirements or our suggestions.
Thirdly customer confirms the samples and places deposit for formal order.
Fourthly We arrange the production.
If you have any other needs, please contact me.
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