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Itopride Hydrochloride for API Intermediates CAS 122892-31-3

China Itopride Hydrochloride for API Intermediates CAS 122892-31-3, Find details about China Medical Supply, Pharmaceutical Chemical from Itopride Hydrochloride for API Intermediates CAS 122892-31-3

Classification
Intermediates & Fine Chemicals
Function
Anti-Spasmodics
Appearance
Powder
Grade Standard
Medicine Grade
Price
Competitive
Delivery
Fast
Storage
Cool Dried Storage
Shelf Life
2 Years
Trademark
IKNOW
Specification
content ≧ 99%
Origin
China
Classification
Intermediates & Fine Chemicals
Function
Anti-Spasmodics
Appearance
Powder
Grade Standard
Medicine Grade
Price
Competitive
Delivery
Fast
Storage
Cool Dried Storage
Shelf Life
2 Years
Trademark
IKNOW
Specification
content ≧ 99%
Origin
China
Itopride Hydrochloride for API Intermediates CAS 122892-31-3
Introduction
 
Product Name:Itopride hydrochloride
Synonyms:Hsr803;N-((4-(2-(dimethylamino)ethoxy)phenyl)methyl)-3,4-dimethoxybenzamidemonohydr;N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4-dimethoxy-benzamide hydrochloride;N-((4-(2-(dimethylamino)ethoxy)phenyl)methyl)-3,4-dimethoxy-benzamidmonohy;N-((4-(2-(dimethylamino)ethoxy)phenyl)methyl)-3,4-dimethoxy-benzamidmonohydrochloride;N-(4-(2-(dimethylamino)ethoxy)benzyl)-3,4-dimethoxidebenzamidehydrochloride;ITOPRIDE HCL;ITOPRIDE HYDROCHLORIDE
CAS:122892-31-3
MF:C20H27ClN2O4
MW:394.89
EINECS:602-905-1
Product Categories:Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Itopride;Amines;Aromatics
Mol File:122892-31-3.Mol
Molecular Structure: Itopride Hydrochloride for API Intermediates CAS 122892-31-3

Itopride, a gastroprokinetic benzamide derivative was launched in Japan for the relief of gastrointestinal symptoms in patients with chronic gastritis.Ltopride is a dopamine D2-receptor antagonist that stimulates acetylcholine (Ach) release on the postganglionic cholinergic neurons to cause Ach accumulation at muscarinic receptors and, therefore, enhances Ach-induced gastric contractions.In animal models, itopride was reported to increase GI transit and gastric emptying.

Chemical Properties
 
Melting point194-1950C
Storage temp.-20ºC Freezer
SolubilityH2O:≥48mg/mL
FormPowder
ColorWhite to tan
Λmax258nm(MeOH)(lit.)

Function

Typically, itopride is indicated in the treatment of GI symptoms caused by reduced GI motility:

• dyspepsia of a non-ulcer/dysmotility type (gastric "fullness", discomfort, and possible pain)
• gastroparesis (delayed gastric emptying)
• anorexia
• heartburn
• regurgitation
• bloating
• nausea and vomiting
• other possible gastric, prolactin, or dopamine related conditions

Itopride is typically taken three times a day. The dose is usually taken on an empty stomach about an hour before meals. However, the dosage and details of administration may vary depending on the patient's age, symptoms, and other factors.
Itopride was shown to significantly improve symptoms in patients with functional dyspepsia and motility disorders in placebo-controlled trials.
These studies concluded that the reduction in the severity of symptoms of functional dyspepsia after 8 weeks of treatment with itopride indicated that itopride was significantly superior to placebo and that itopride yielded a greater rate of response than placebo in significantly reducing pain and fullness.
 
Packing & Shipment
 
Itopride Hydrochloride for API Intermediates CAS 122892-31-3


Itopride Hydrochloride for API Intermediates CAS 122892-31-3Itopride Hydrochloride for API Intermediates CAS 122892-31-3

Quality Control of Health Sources

1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards.
5) Warehousing and storage:Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.

Itopride Hydrochloride for API Intermediates CAS 122892-31-3


Certification

Itopride Hydrochloride for API Intermediates CAS 122892-31-3

Itopride Hydrochloride for API Intermediates CAS 122892-31-3

Itopride Hydrochloride for API Intermediates CAS 122892-31-3
 
Q1:Which kind of payment terms do you accept?
For small order,you can pay by T/T or Western Union ,nomal order by T/T to our company account.

Q2:Can you give me a discount price?
Surely,It depend on your quantity.

Q3:How can I get a sample?
Free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.

Q4:How to confirm the Product Quality before placing orders?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q5:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero.If there is a real quality problem caused by us, we will send you free goods for replacement or refund you

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