Manufacturer Supply CAS 21187 -98-4 Gliclazide

China Manufacturer Supply CAS 21187-98-4 Gliclazide, Find details about China Gliclazide, 21187-98-4 from Manufacturer Supply CAS 21187-98-4 Gliclazide

Model NO.
TY-02ALI
CAS No.
21187-98-4
Appearance
White Powder
Einecs
616-396-9
Assay
99%
Shelf
2 Years
Trademark
tongyon
Transport Package
25kg/Drum 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Origin
China
Model NO.
TY-02ALI
CAS No.
21187-98-4
Appearance
White Powder
Einecs
616-396-9
Assay
99%
Shelf
2 Years
Trademark
tongyon
Transport Package
25kg/Drum 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Origin
China
Manufacturer Supply CAS 21187-98-4 Gliclazide
Manufacturer Supply CAS 21187-98-4 Gliclazide

Manufacturer Supply CAS 21187-98-4 Gliclazide
 
Product nameGliclazide 
CAS21187-98-4
Appearancewhite powder
Assay99%
StorageCool and Protect from light


Manufacturer Supply CAS 21187-98-4 Gliclazide

Product Name:Gliclazide
CAS:21187-98-4
MF:C15H21N3O3S
MW:323.41
EINECS:244-260-5
Mol File:21187-98-4.mol  
Melting point:163-169 °C(lit.)
Density 1.2205 (rough estimate)
refractive index 1.6740 (estimate)
storage temp. -20°C Freezer
solubility methylenee chloride: soluble
pka6.07±0.10(Predicted)
form powder
color white


Manufacturer Supply CAS 21187-98-4 Gliclazide


liclazide is an oral antihyperglycemic agent used for the treatment of diabetes mellitus type II. It belongs to the sulfonylurea class of insuline secretagogues, which stimulates β cells of the pancreas to release insuline. Gliclazide binds to the β cell sulfonyl urea receptor (SUR1), further blocking the ATP sensitive potassium channels. Therefore, the potassium efflux substantially decreases, causing depolarization of the β cells. Then the voltage-dependent calcium channels in the β cell are open, resulting in calmodulin activation, which in turn leads to exocytosis of insuline containing secretorty granules. Recent studies have also shown that gliclazide can effectiveimprove anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes and protect pancreatic beta-cells from damage by hydrogeen peroxide.


GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.


Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.


Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.


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