Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7

China Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7, Find details about China Cheap Price Clobetasol Propionate, Quality Control Clobetasol Propionate from Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7

Model NO.
Clobetasol propionate
Appearance
White Crystalline Solid Powder
CAS Number
CAS No.25122-46-7
Molecular Formula
C25h32clfo5
Molecular Weight
466.970
Coa
Provided
Grade Standard
Feed Grade, Food Grade, Medicine Grade
Melting Point
195.5-197ºC
Boiling Point
569.0±50.0 °c at 760 Mmhg
Density
1.3G/Cm3
Other Name
Dermovat/Clobetasole Propionate
Einecs No.
246-634-3
Trademark
ORIHERB
Transport Package
Aluminum Foil Bag; Fiber Drum
Specification
99.5%
Origin
China
Model NO.
Clobetasol propionate
Appearance
White Crystalline Solid Powder
CAS Number
CAS No.25122-46-7
Molecular Formula
C25h32clfo5
Molecular Weight
466.970
Coa
Provided
Grade Standard
Feed Grade, Food Grade, Medicine Grade
Melting Point
195.5-197ºC
Boiling Point
569.0±50.0 °c at 760 Mmhg
Density
1.3G/Cm3
Other Name
Dermovat/Clobetasole Propionate
Einecs No.
246-634-3
Trademark
ORIHERB
Transport Package
Aluminum Foil Bag; Fiber Drum
Specification
99.5%
Origin
China
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Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7
Product Name:Clobetasol
 
Other NameDermovat/CLOBETASOLE PROPIONATE
 
CAS:25122-41-2
 
MF:C22H28ClFO4
 
MW:466.970
 
Purity:99%min
 
Shelf Life2 years
 
Appearancewhite crystalline powder
 
Brand Name:Oriherb
 
FormPowder
 
Place of Origin:Shaanxi, China (Mainland)
 
Packaging:Bottle, Can, Drum, Plastic Contain
 
Standard:USP EP JP etc.
 
Introduction:Clobetasol propionate is a corticosteroid used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to ivy/oak.
Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available. It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). It is also used to treat several autoimmune diseases including alopecia areata, vitiligo and lichen planus (auto immune skin nodules).


Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7

 

 

Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7

Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7

Adrenocorticotropic hormone drugs, anti-inflammatory, anti-allergic and anti-drug more effective than prednisone, and promoting the removal of potassium sodium retention is very light, intramuscular or intravenous pituitary - adrenal strong inhibition:
1. Anti-inflammatory effects: The product can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. Hormone suppression of inflammatory cells, including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis, lysosomal enzyme release and synthesis and release of inflammatory chemical mediators. Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. 
2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response. Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins.

Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7

Suitable for eczema, neurodermatitis, psoriasis, chronic palmoplantar Pustulosis, Lichen Planus, Discoid Lupus Erythematosus effectively treatedby external use of glucocorticoids, such as itching and noninfectiousinflammatory skin diseases.

 

Test items

Standard

Result

Description

White to off- White powder

Conforms

 

Identification

IR

IR spectrum of sample is the same as working standard

Conforms

HPLC

HPLC RT of the sample is the same as the working standard

Conforms

Melting point

165.0°C~169.0°C

165.8°C~167.0°C

Optical rotation

-23°~-29°

-27.4°

Loss on drying

NMT 1.0 %

0.17%

Residue on ignition

NMT 0.1 %

0.03%

Heavy metals

NMT 20ppm

Conforms

Related substances

Impurity A

NMT 0.1 %

Not detected

Impurity B

NMT 0.1 %

Not detected

Impurity C

NMT 0.1 %

0.02%

Single impurity

NMT 0.2 %

0.17%

Total impurity

NMT 1.0 %

0.60%

Assay

NLT 99.0%

99.0%


Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7


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Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7



Packaging & Shipping Detail


Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7
Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7



Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7









Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7






Factory Supply Clobetasol Propionate Powder CAS No. 25122-46-7