High Quality Chemical Raw Materials ACP196 CAS No: 1420477-60-6 Acalabrutinib
China High Quality Chemical Raw Materials ACP196 CAS No: 1420477-60-6 Acalabrutinib, Find details about China Acalabrutinib, CAS No: 1420477-60-6 from High Quality Chemical Raw Materials ACP196 CAS No: 1420477-60-6 Acalabrutinib
Basic Info.
| Min. Order: | 25 kg |
|---|---|
| Port: | Hong Kong, Hong Kong
|
| Production Capacity: | 10000kg/Year |
| Payment Terms: | L/C, T/T, D/P, Western Union, Money Gram |
| Transport Package: | Bucket |
|---|---|
| Specification: | 25KG/ bucket |
| Origin: | Wuhan |
Product Desciption
English name :ACP196
English synonyms :ACP196; ACP-196; acalabrutinib; 4 - [Benzamide, 8 - amino - 3 - [(2 s) - 1 - (1 - oxo - 2 - butyn - 1 - yl) - 2 - pyrrolidinyl] imidazo [1, 5 - a] pyrazin - 1 - yl] - N - 2 - pyridinyl -; ACP196,Acalabrutinib; 8 - Amino - 4 - [3 - [(2 s) 1 - (1 - oxo - 2 - butyn - 1 - yl) - 2 - pyrroChemicalbooklidinyl] imidazo [1, 5 - a] pyrazin - 1 - yl] - N - 2 - pyridinylbenzamide; EOS-60753; (S) - 4 - (8 - amino - 3 - (2 - ynoylpyrrolidin - 2-1 - but - yl) imidazo [1, 5 - a] pyrazin - 1 - yl) - N - (pyridin - 2 - yl) benzamide
CAS no. : 1420477-60-6
Molecular formula: C26H23N7O2
Molecular weight: 465.51
EINECS no. : 814-272-0
Density: 1.37± 0.1g /cm3(Predicted)
Acidity coefficient (pKa) : 11.47±0.70(Predicted)
Acatinib uses and synthesis methods
Acalabrutinib(ACP-196) is a selective second-generation BTK inhibitor that inhibits the activation of B cell surface protoantibody signaling pathways. It has good target specificity and is 323-,94-,19-,9- times more selective for BTK than other TEC kinase family members such as ITK, TXK, BMK and TEC. No activity for EGFChemicalbookR.
Use: ACP-196 is an investigational anticancer drug that is a selective Bruton tyrosine kinase (BTK) inhibitor. This kinase transmits signals from the B cell receptor (BCR), so any inherited BTK mutation causes B cell immune deficiency. Therefore, BTK inhibitors targeting B cell signaling have shown great promise in the treatment of chronic lymphocytic leukemia (CLL).
English synonyms :ACP196; ACP-196; acalabrutinib; 4 - [Benzamide, 8 - amino - 3 - [(2 s) - 1 - (1 - oxo - 2 - butyn - 1 - yl) - 2 - pyrrolidinyl] imidazo [1, 5 - a] pyrazin - 1 - yl] - N - 2 - pyridinyl -; ACP196,Acalabrutinib; 8 - Amino - 4 - [3 - [(2 s) 1 - (1 - oxo - 2 - butyn - 1 - yl) - 2 - pyrroChemicalbooklidinyl] imidazo [1, 5 - a] pyrazin - 1 - yl] - N - 2 - pyridinylbenzamide; EOS-60753; (S) - 4 - (8 - amino - 3 - (2 - ynoylpyrrolidin - 2-1 - but - yl) imidazo [1, 5 - a] pyrazin - 1 - yl) - N - (pyridin - 2 - yl) benzamide
CAS no. : 1420477-60-6
Molecular formula: C26H23N7O2
Molecular weight: 465.51
EINECS no. : 814-272-0
Density: 1.37± 0.1g /cm3(Predicted)
Acidity coefficient (pKa) : 11.47±0.70(Predicted)
Acatinib uses and synthesis methods
Acalabrutinib(ACP-196) is a selective second-generation BTK inhibitor that inhibits the activation of B cell surface protoantibody signaling pathways. It has good target specificity and is 323-,94-,19-,9- times more selective for BTK than other TEC kinase family members such as ITK, TXK, BMK and TEC. No activity for EGFChemicalbookR.
Use: ACP-196 is an investigational anticancer drug that is a selective Bruton tyrosine kinase (BTK) inhibitor. This kinase transmits signals from the B cell receptor (BCR), so any inherited BTK mutation causes B cell immune deficiency. Therefore, BTK inhibitors targeting B cell signaling have shown great promise in the treatment of chronic lymphocytic leukemia (CLL).
You Might Also Like
Inch Size R Series Open-Zz-2RS Deep Groove Ballbearings R144......
Dried Mealworms for Tropicl Fish
Wc67k Series Economic Type CNC Hydraulic Press Brake
White Cranked Espag UPVC Window Hardware Handle
VFD 37kw/45kw 380V Inverter Torque Control Motor Frequency I......
0.9mx9m 14mm Multiple Color PVC Coil Plastic Mat
Stainless Steel Broken Reverse Twill Dutch Weave Wire Mesh 1......
Factory Price of Sodium Pyrrolidone Carboxylate CAS 28874 -5......
60Hz 1800rpm 50kVA/40kw Perkins Engine Diesel Generator Set ......
Blue Simple Rubber Squeeze Shower Duck
Jaw Crusher Low Price Mining Crushing Machine Zhengzhou
25mm Sturdy Steel Cam Buckles Motorbike Tie-Down Straps Asse......