Function

Indications: Anxiety depression used to treat mild, moderate or severe depression, neurogenic and reactive depression, somatic and gastrointestinal discomfort, and anxiety depression in alcohol-dependent patients during withdrawal.
Adverse effects:
Adverse reactions are common in dry mouth, nausea, lethargy, dizziness, headache, insomnia, nightmares, weight gain, constipation. Myalgia, back pain, ventricular arrhythmia, postural hypotension, palpitations, heart rate slowdown, Tremor, anxiety, Yijire, hot flashes, facial redness, stomachache, flatulence, abdominal pain, serum alanine aminotransferase, rash, etc.

Tianeptine sodium salt is a salt of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake. Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation.