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99% Purity Lisinopril Pharmaceutical Intermediate Chemical CAS 83915-83-7

China 99% Purity Lisinopril Pharmaceutical Intermediate Chemical CAS 83915-83-7, Find details about China Lisinopril, Lisinopril Dlhydrate from 99% Purity Lisinopril Pharmaceutical Intermediate Chemical CAS 83915-83-7

Model NO.
CAS 83915-83-7
CAS
83915-83-7
Appearance
White Crystalline Powder.
Mf
C21h31n3o5
Test
HPLC
Storage
Cool Dry Place
Shelf Life
2 Years Proper Storage
Application
Pharmaceutical Intermediates
Trademark
HH
Transport Package
1kg Per Foil Bag, 20kg Per Drum
Specification
99%
Origin
Nanjing
HS Code
2934999090
Model NO.
CAS 83915-83-7
CAS
83915-83-7
Appearance
White Crystalline Powder.
Mf
C21h31n3o5
Test
HPLC
Storage
Cool Dry Place
Shelf Life
2 Years Proper Storage
Application
Pharmaceutical Intermediates
Trademark
HH
Transport Package
1kg Per Foil Bag, 20kg Per Drum
Specification
99%
Origin
Nanjing
HS Code
2934999090

Product Description

 

99% Purity Lisinopril Pharmaceutical Intermediate Chemical CAS 83915-83-7
What is Lisinopril ?

Lisinopril is a third-generation angiotensin-converting enzyme inhibitor and a lysine derivative of enalapril. It was marketed in the United States in 1987 for the treatment of hypertension and is a first-line antihypertensive drug . The pharmacological action characteristics are similar to Enalapril (Enalapril), with strong angiotensin-converting enzyme inhibitory effect, quick onset and long action time, just take the medicine once a day. The inhibitory effect on ACE is 6 to 8 times that of captopril and 1 to 3 times that of benazepril. I
Function and Application 

Angiotensin Converting Enzyme Inhibitor (ACE-I), a lysine derivative of Enalapril, is the third non-sulfhydryl group in the world to be marketed. ACE-I. Long-acting, once a day, and the dosage is only 1/20 of captopril, 1/4 of enalapril, oral bioavailability is better. The curative effect is remarkable. For moderate and severe patients, the Chemicalbook should be better than captopril and enalapril. It has no direct effect on the heart, does not cause arrhythmia, has no central effect, and has no adverse reactions such as blood pressure rebound. It can be used for diseases accompanied by diabetes, asthma, peripheral vascular disease, psychosis and congestive heart failure, and for other diseases Patients with hypertension who are contraindicated in the treatment of drugs. It is effective for short-term and long-term congestive heart failure.
 
Product NameLisinopril dlhydrate
ReferenceUSP
TestSpecificationResults
CharactersWhite crystalline powder.White crystalline powder.
Identification1) Infrared absorption spectrum concordant with spectrum obtained with Lisinopril dihydrate RS.Conform
2) The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that of the Standard preparation obtained as directed in the Assay.Conform
Specific optical rotation [a]Hg25-115.3-122.5°-119.6°
Water8.0~9.5%8.3%
Residue on ignition≤0.1%<0.1%
Assay (HPLC)98.0-102.0% (calculated on anhydrous basis)98.6%
Residual solventsEthanol≤0.5%0.017%
Related substances (HPLC)DL-Homophenylalanine ≤0.30%<RL(RL:0.05%)
Related compound A ≤0.3%<RL(RL:0.05%)
R,S,S-Diketopiperazine ≤0.3%<LOD(LOD:0.01%)
Lisinopril epimer ≤0.3%0.07%
Lisinopril cyclohexyl analogue ≤0.30%0.08%
N-Alkyl-L-lysine ≤0.3%0.09%
N-Alkyl lisinopril ≤0.15%<LOD(LOD:0.01%)
Any individual unspecified impurity≤0.10%<RL(RL:0.05%)
Total imp. does not include lisinopril epimer≤0.5%0.17%
ConclusionComplies with USP
 
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99% Purity Lisinopril Pharmaceutical Intermediate Chemical CAS 83915-83-7

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 99% Purity Lisinopril Pharmaceutical Intermediate Chemical CAS 83915-83-7

 

FAQ
Q1:Can you give me a discount price?
A1:Sure, it depends on your quantity.
Q2: What about the lead time? 
A2:Sample needs 3-5 days, mass production time needs 1-2 weeks for order quantity.
Q3:How do you control the quality? 
A3:We will make samples before mass production, and after sample approved, we will begin bulk production.
Q4:How do you ship the goods and how long does it take to arrive? 
A4:We usually ship by UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional.
Q5:What is you terms of payment?
A5:Our normal payment term is T/T 30% deposit after order signed and 70% before shippment.
Q6:Is there cheap shipping cost to import to our country? 
A6:For small order, express will be best. And for bulk order, sea ship way is best but take much time.
 

 

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