Gamithromycin is a new kind of semi-synthetic Marolides veterinary antibiotic, which can inhibit the synthesis of RNA-dependent protein in bacteria and play a role in bacteriostasis and sterilization. Gamimicin has high antibacterial activity against hemolytic Mann's Bacillus, Pasteurella multocida and Mycoplasma bovis, which cause bovine respiratory diseases (BRD). It has the advantages of wide antibacterial spectrum, strong antibacterial activity, rapid absorption, wide distribution in vivo, low residue in vivo and high safety. It is widely used in clinical treatment of bovine respiratory diseases caused by bacterial pathogens such as Pasteurella haemolytica, Pasteurella haemorrhagica and histophile abroad.