China Nice Price CAS 151533-22-1 99% L 5 Methyltetrahydrofolate Calcium, Find details about China L 5 Methyltetrahydrofolate Calcium, L-5-Methyltetrahydrofolate Calcium from Nice Price CAS 151533-22-1 99% L 5 Methyltetrahydrofolate Calcium
Name: L-5-Methyltetrahydrofolate calcium
Other name:L-5-Methyletrahydrofolatecalciumsalt; Levomefolate calcium
CAS#:151533-22-1
Appearance:Off-White to Pale Yellow Solid
Assay:99%
Mol.Formula:C20H23CaN7O6
Mol.Weight:497.52
Melting Point: >300°C
Item | Standard |
Appearance | White to yellow or beige powder |
Assay(On dry basis as Ca salt) | 97.0%-102.0% |
Specific Rotation(C=1.5%in water,25ºC) | +14.5~+18.50 |
Calcium(Anhydrous basis) | 7.0%-8.5% |
D-Methylfolate | ≤1.0% |
Chloride | ≤0.5% |
Water (K-F) | ≤16.0% |
Single impurity | ≤1.0% |
Residual solvent(Ethanol) | ≤5000ppm |
Chloride(Cl) | ≤0.5% |
As | ≤1ppm |
Heavy Metals | ≤20ppm |
Total plate count | ≤100cuf/g |
Mold & Yeasts | ≤100cuf/g |
Salmonella | Negative |
E. Coil | Negative |
1. L-5-methyltetrahydrofolate calcium is mainly for folic acid antagonists (such as methotrexate, pyrimethamine, benzyl cefalexin and trimethoprim) antidote, it's usually used for prevention of methotrexate dose or overdose treatment caused severe toxic effects.
2. L-5-methyltetrahydrofolate calcium is for folic acid treatment of the following diseases, such as inflammatory diarrhea and protein-energy malnutrition (poor nutrition), pregnancy or infancy megaloblastic anemia caused by poor.
3. L-5-methyltetrahydrofolate calcium as adjuvant therapy for colon cancer, rectal cancer.
4. L-5-methyltetrahydrofolate calcium combined with 5-FU and treatment of digestive tract tumors or other 5-FU-sensitive tumors. High-dose CF used in conjunction with 5-FU (LF), the basic programme is currently the treatment of colon and rectal cancer.
5. L-5-methyltetrahydrofolate calcium for children with leukemia, lymphoma, and osteosarcoma, such as high dose MTX treatment when rescued.
The calcium salt of (6S)-5-methyltetrahydrofolic acid, l-5-methyltetrahydrofolate calcium which belongs to the groupof folate vitamins (Vitamin B9, Folacin).