High Quality Levomefolic Acid CAS 31690-09-2

China High Quality Levomefolic Acid CAS 31690-09-2, Find details about China 31690-09-2 Levomefolic Acid, CAS 31690-09-2 from High Quality Levomefolic Acid CAS 31690-09-2

Basic Info.

Model NO.

31690-09-2

Storage Condition

Store at Rt

Trademark

Fousi

Transport Package

Aluminium Foil Bag

Specification

Origin

China

Model NO.

31690-09-2

Storage Condition

Store at Rt

Trademark

Fousi

Transport Package

Aluminium Foil Bag

Specification

Origin

China

Product Desciption

High Quality Levomefolic Acid CAS 31690-09-2

Levomefolic acid (INN) (also known as L-5-MTHF, L-methylfolate and L-5-methyltetrahydrofolate and (6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine.

It is also the form found in circulation and transported across membranes into tissues and across the blood-brain barrier. In the cell, L-methylfolate is used in the methylation of homocysteine to form methionine and tetrahydrofolate (THF).

THF is the immediate acceptor of one carbon units for the synthesis of thymidine-DNA, purines (RNA and DNA) and methionine.

The un-methylated form, folic acid (vitamin B9), is a synthetic form of folate, and must undergo enzymatic reduction by methylenetetrahydrofolate reductase (MTHFR) to become biologically active.

High Quality Levomefolic Acid CAS 31690-09-2

Functions:

Major depressive disorder
Preliminary research suggests that levomefolic acid (L-methylfolate) taken with a first-line antidepressant may provide an adjunctive antidepressant effect for individuals who do not respond or have only a partial therapeutic response to SSRI or SNRI medication, and might be a more cost-effective adjunctive agent than second-generation antipsychotics.

Cardiovascular disease and cancer
Levomefolic acid (and folic acid in turn) has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers. It bypasses several metabolic steps in the body and better binds thymidylate synthase with FdUMP, a metabolite of the drug fluorouracil.

High Quality Levomefolic Acid CAS 31690-09-2