Forme stanes is a second generation, irreversible, steroidal aromatase inhibitor. It inhibits the aromatase enzyme responsible for converting androgens to estrogens, thereby preventing estrogen production. Breast cancer may be estrogen sensitive or insensitive. A majority of breast cancers are estrogen sensitive. Estrogen sensitive breast cancer cells depend on estrogen for viability. Thus removal of estrogen from the body can be an effective treatment for hormone sensitive breast cancers.

Forme stanes has been targeted specifically for the treatment of postmenopausal women. Unlike premenopausal women who produce most estrogen in the ovaries, postmenopausal women produce most estrogen in peripheral tissues with the help of the aromatase enzyme. Forme stanes, an aromatase inhibitor, can thus help to decrease the local production of estrogen by blocking the aromatase enzyme in peripheral tissues (ie. Adispose tissue of the breast) to treat hormone sensitive breast cancer.

1.Aromatase inhibitors. For progressive breast cancer.

2. This product is an aromatase inhibitor. It is similar to Amino glute thimide. It has a stronger selective inhibitory effect on type I aromatase. The mechanism of this product's enzyme inhibition is through the active part of the carcass mother nucleus and enzyme. Combining with the normal enzymatic hydrolysate -----Estrogen dione competes with the active site, resulting in suicide inhibition, so that the aromatase is inactivated forever. This product is 60 times stronger than the amino glute thimide in vitro. For the treatment of postmenopausal women with advanced breast tumors. Its toxic side effects are small and well tolerated.