China Local Anesthetics Algesia Celecoxib Powder CAS: 169590-42-5 Celecoxib, Find details about China Celecoxib, Celecoxib Powder from Local Anesthetics Algesia Celecoxib Powder CAS: 169590-42-5 Celecoxib
The Leader Manufacturer of Powder-TGY Bioteach
Celecoxib is a selective Cox-2(cyclooxygenase-2) inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LMP1 (IC50 of 61.31 μM).Celecoxib
Celecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people .
Product name | Celecoxib | Origin | China |
CAS | 169590-42-5 | Grade | Medical grade |
Test | Specifications |
Appearance | White to off-white crystalline powder. |
Freely soluble in methanol,ethanol,acetone and dimethyl sulfoxide, practically insoluble in water. | |
Melting Point | 160.0~164.0ºC |
Identification | A.The infrared absorption spectrum should meet with the reference spectrum |
B.The retention time of sample major peak should meet with the retention time of reference substance major peak. | |
Water | ≤0.5% |
Residue On Ignition | ≤0.2% |
Heavy Metal | ≤20ppm |
Fluorine | 14.2%~16.4% |
Related substances | Any individual impurity≤0.5% |
Total impurities≤1.0% | |
Residual Solvent | complies |
Assay(on dried basis) | 98.0% ~102.0% |
Conclusion | Conform with specification |
Storage | Store in sealed containers at cool & dry place. |
| Protect from light, moisture and pest infestation. |
Shelf life | 2 years when properly stored |
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Celecoxib is used for osteoarthritis, rheumatoid arthritis, acute pain, musculoskeletal pain, painful menstruation, ankylosing spondylitis, and to reduce the number of colon and rectal polyps in people with familial adenomatous polyposis.It may also be used in children with juvenile rheumatoid arthritis who are older than two years of age and weigh more than 10 kg (22 lb).
For postoperative pain, it is more or less equal to ibuprofen. For pain relief, it is similar to paracetamol (acetaminophen).And in osteoarthritis, acetaminophen is the first line treatment.In knee and hip osteoarthritis, acetaminophen may be ineffective.
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XIAN Tian Guangyuan Biotech Co.,Ltd.Was founded in May 2003, is a professional animal and plant Extracts
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areas have a strong strength.The company is headquartered in the outskirts of Xi'an, under research and
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