China Pharmaceutical Raw Material CAS 169590-42-5 Celecoxib Powder, Find details about China Celecoxib, Celecoxib Powder from Pharmaceutical Raw Material CAS 169590-42-5 Celecoxib Powder
Celecoxib is a selective Cox-2(cyclooxygenase-2) inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LMP1 (IC50 of 61.31 μM).
Celecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people.
Product Name | Celecoxib |
Synonyms | Celebra |
CAS No. | 169590-42-5 |
Molecular Formula | C17H14F3N3O2S |
Molecular Weight | 381.37200 |
EINECS NO. | 685-962-5 |
Purity | 99% |
Appearance | White powder |
Certificate of Analysis
Item | Specification |
Assay | >98% |
Appearance | White powder |
Odor | Characteristic |
Taste | Characteristic |
Particle Size | NLT 100% Through 80 mesh |
Loss on Drying | <2.0% |
Heavy metals | ≤10ppm |
Arsenic | ≤3ppm |
Lead | ≤3ppm |
<2.0% | |
Total Plate Count | ≤1000cfu/g |
Total Yeast & Mold | ≤100cfu/g |
E.Coli | Negative |
Salmonella | Negative |
Functions & Application
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.
Celecoxib is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain.
Celecoxib is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is also used in the treatment of hereditary polyps in the colon.
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