China Anti-Virus Powder Chloroquine CAS 54-05-7/54057/54 05 7/50-63-5 Chloroquine Phosphate, Find details about China 54-05-7, Research Chemical from Anti-Virus Powder Chloroquine CAS 54-05-7/54057/54 05 7/50-63-5 Chloroquine Phosphate
Melting point | 87° |
Boiling point | 475.41°C (rough estimate) |
density | 1.0500 (rough estimate) |
refractive index | 1.6010 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
Description | Chloroquine is the most effective of the hundreds of 4-aminoquinolines synthesized and tested during World War II as potential antimalarials. Structure-activity relationships demonstrated that the chloro at the 8-position increased activity, whereas alkylation at C-3 and C-8 diminished activity. The replacement of one of its N-ethyl groups with an hydroxyethyl produced hydroxychloroquine, a compound with reduced toxicity that is rarely used today except in cases of rheumatoid arthritis. |
Chemical Properties | solid |
Uses | Medicine (antimalarial). Usually dispensed as the phosphate. |
CQ and HCQ are both used as anti-inflammatory and antimalarial drugs. |
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