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Isoprinosine CAS 36703 -88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 Roflumilast

China Isoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 Roflumilast, Find details about China Isoprinosine, CAS 36703-88-5 from Isoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 Roflumilast

Model NO.
Roflumilast
CAS
162401-32-3
Mf
C17h14cl2f2n2o3
MW
403.21
Appearance
White Powder
Function
Biological and Pharmaceutical Intermediates
Shelf Life
2 Years
Test Method
HPLC UV
Storage
Cool Dry Place
Payment
Tt.Western Union .Credit Card.Moneygram
Delivery Time
Within 2 Days
Certificate
COA MSDS
Sample
Available
Trademark
Faithful
Transport Package
Aluminum Foil Bag Packaging
Specification
10g/bag; 100g/bag; 1kg/bag
Origin
China
Model NO.
Roflumilast
CAS
162401-32-3
Mf
C17h14cl2f2n2o3
MW
403.21
Appearance
White Powder
Function
Biological and Pharmaceutical Intermediates
Shelf Life
2 Years
Test Method
HPLC UV
Storage
Cool Dry Place
Payment
Tt.Western Union .Credit Card.Moneygram
Delivery Time
Within 2 Days
Certificate
COA MSDS
Sample
Available
Trademark
Faithful
Transport Package
Aluminum Foil Bag Packaging
Specification
10g/bag; 100g/bag; 1kg/bag
Origin
China
Isoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 RoflumilastIsoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 methyl vanillin//CAS 162401-32-3 Roflumilast

Introduction

Product NameRoflumilast
CAS No162401-32-3
AppearanceWhite  Powder
Shelf Life2 Years
Function/

Roflumilast is a selective, orally active PDE4 inhibitor thatwas approved in Germany in July 2010 as an add-on to bronchodilator treatment for maintenance therapy of severe chronic obstructive pulmonary disorder (COPD) associated with chronic bronchitis in adult patients with a history of frequent exacerbations .
Function

Roflumilast has antiinflammatory effects and is under development as an orally administered drug for the treatment of
inflammatory conditions of the lungs such as asthma, and chronic obstructive pulmonary disease (COPD).
It is a selective phosphodiesterase 4 (PDE4) (IC50 = 0.8 nM) inhibitor. Inhibition of PDE4 prevents the hydrolysis of
phosphodiesters, which play a key role in signal transduction. This compound has anti-inflammatory properties and is particularly effective at reducing inflammation in lung tissue.

Specification
ItemsStandardsResults
AppearanceWhite or off-white solid powderComplies
IdentificationBy IRComplies
By HPLCComplies
SolubilityHighly soluble in methanol,soluble in
ethanol,acetonitrile; slightly soluble in water		Complies
Melting Point156ºC~160ºC157.6ºC~158.5ºC
Water Content≤ 0.50%0.25%
Residue on Ignition≤ 0.10%0.05%
Heavy Metal≤10ppmComplies
Residual SolventsDichloromethane: ≤100ppmND
Hexane: ≤200ppmND
Ethyl acetate: ≤500ppmND
Tetrahydrofuran: ≤100ppmND
Related SubstancesImpurity A: ≤0.10%0.07%
Impurity B: ≤0.10%0.08%
Any other single impurity: ≤0.10%0.08%
Total Impurities: ≤0.50%0.15%
Assay
(HPLC basis on drying)		98.0%~102.0%99.99%
Isoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 Roflumilast
Isoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 RoflumilastIsoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 RoflumilastIsoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 RoflumilastIsoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 RoflumilastIsoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 RoflumilastIsoprinosine CAS 36703-88-5//Sucralfate CAS 54182-58-0//Ulipristal Acetate CAS 126784-99-4//Veratraldehyde 120-14-9 Methyl Vanillin//CAS 162401-32-3 Roflumilast

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