Pharmaceutical Inosine Purity Inosine Powder Material Inosine
China Pharmaceutical Inosine Purity Inosine Powder Material Inosine, Find details about China Inosine, Material Inosine from Pharmaceutical Inosine Purity Inosine Powder Material Inosine
Basic Info.
Model NO.
D-Sung Inosine
Product Name
Inosine
Name
Inosine Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical Grade
Specific
COA
Test Method
HPLC
Mf
C10h12n4o5
CAS
58-63-9
MW
268.22608
Density
2.08
Boiling Point
732.8
Melting Point
212
Trademark
D-Sung
Transport Package
Negotiabie
Specification
99%
Origin
Xi′an Shaanxi
Model NO.
D-Sung Inosine
Product Name
Inosine
Name
Inosine Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical Grade
Specific
COA
Test Method
HPLC
Mf
C10h12n4o5
CAS
58-63-9
MW
268.22608
Density
2.08
Boiling Point
732.8
Melting Point
212
Trademark
D-Sung
Transport Package
Negotiabie
Specification
99%
Origin
Xi′an Shaanxi
Product Desciption
Pharmaceutical Inosine Purity Inosine Powder Material Inosine
| Product Name: | Inosine |
| CAS: | 58-63-9 |
| MF: | C10H12N4O5 |
| MW: | 268.23 |
| EINECS: | 200-390-4 |
Inosine, an endogenous purine nucleoside, has immunomodulatory, neuroprotective, and analgesic properties. In vitro: Inosine has been shown to stimulate axonal growth in cell culture and promote corticospinal tract axons to sprout collateral branches after stroke, spinal cord injury and TBI in rodent models.[1] Inosine dose-dependently stimulates cAMP production mediated through the A2AR. Inosine dose-dependently induces A2AR-mediated ERK1/2 phosphorylation.[2] In vivo: The reference for Inosine is 1 or 10 mg/kg, i.p. Preventive treatment with inosine inhibits the development and progression of EAE in C57Bl/6 mice. neuroinflammation and demyelinating processes are blocked by inosine treatment. Additionally, inosine consistently inhibits IL-17 levels in peripheral lymphoid tissue, as well as IL-4 levels and A2AR up-regulation in the spinal cord, likely, through an ERK1-independent pathway. [3] inosine acting through adenosine receptors (ARs) exerts a wide range of anti-inflammatory and immunomodulatory effects in vivo.
1. Used in the treatment of leucopenia and thrombocytopenia.
2. In the treatment of acute hepatitis and chronic hepatitis and liver cirrhosis, hepatic encephalopathy.
3. Used for coronary atherosclerotic heart disease (coronary heart disease), myocardial infarction,
rheumatic heart disease, cor pulmonale auxiliary drug use.
4. Used to prevent and mitigate the schistosomiasis prevention drugs caused by the heart and the liver toxicity.
5. Used for eye diseases (central retinal inflammation, optic atrophy) auxiliary drug use.
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