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High Purity Pirfenidone Powder CAS 53179-13-8

China High Purity Pirfenidone Powder CAS 53179-13-8, Find details about China Pirfenidone, CAS 53179-13-8 from High Purity Pirfenidone Powder CAS 53179-13-8

Model NO.
VZ2020027
Product Name
Pirfenidone
CAS
53179-13-8
Molecular Formula
C12h11no
Molecular Weight
185.22
Einecs
621-260-7
Density
1.137±0.06 g/cm3(Predicted)
Appearance
White Powder
Shelf Life
2 Years
Grade
Medicine Grade
Transport Package
Bag/Drum
Specification
0.01Kg~5Kg/bag
Origin
Hubei, China
Model NO.
VZ2020027
Product Name
Pirfenidone
CAS
53179-13-8
Molecular Formula
C12h11no
Molecular Weight
185.22
Einecs
621-260-7
Density
1.137±0.06 g/cm3(Predicted)
Appearance
White Powder
Shelf Life
2 Years
Grade
Medicine Grade
Transport Package
Bag/Drum
Specification
0.01Kg~5Kg/bag
Origin
Hubei, China
Product name
Pirfenidone
CAS NO
53179-13-8
MF
C12H11NO
MW
185.22
EINECS:
621-260-7
Appearance
White fine powder
Assay
98%min
High Purity Pirfenidone Powder CAS 53179-13-8

What is pirfenidone?
Pirfenidone is used to treat a lung disease called idiopathic pulmonary fibrosis (IPF). IPF causes scar tissue to form deep within your lungs. The scar tissue thickens and becomes stiff or thick over time, which can make it harder for your lungs to work. Decreased lung function can make it hard for you to breathe. Other medical problems can occur when your brain, heart, and other organs do not get enough oxygen.
The cause of IPF is often unknown, but this condition is a progressive disease that can be fatal. Pirfenidone is not a cure for IPF, but this medicine may slow the progress of this disease.

Function:
Pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement,reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.

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