China Anti -Lyric/Aeg1 Rabbit Polyclonal Primary Antibodies, Find details about China Polyclonal Primary Antibodies, Primary Polyclonal Antibody from Anti -Lyric/Aeg1 Rabbit Polyclonal Primary Antibodies
Description | LYRIC rabbit polyclonal |
Protein full name | Protein LYRIC |
Synonyms | 3D3/LYRIC, Lysine-rich CEACAM1 co-isolated protein, Metadherin, Metastasis adhesion protein, Mtdh, Lyric |
Immunogen | Recombinant protein corresponding to Mouse LYRIC |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Cytoplasm, Nucleus |
Uniprot ID | Q86UE4, Q80WJ7, Q9Z1W6 |
Applications
Applications | IHC | IF |
Species | Human, Mouse, Rat | Human, Mouse, Rat |
Dilution | 1: 1500-1: 3000 | 1: 1500-1: 3000 |
Positive tissue | colon cancer, testis, spinal cord, kidney, brain | colon cancer, breast cancer, brain, testis, lung, skin, heart |
Background
LYRIC, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22 , the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression.
Images
Immunohistochemistry analysis of paraffin-embedded human colon cancer using LYRIC (GB111269) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded mouse testis using LYRIC (GB111269) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded mouse spinal cord using LYRIC (GB111269) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded mouse kidney using LYRIC (GB111269) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded rat brain using LYRIC (GB111269) at dilution of 1: 2000 | |
Immunofluorescent analysis of paraformaldehyde-fixed human colon cancer using LYRIC (GB111269) at dilution of 1: 2000 |
Storage
Storage | Store at -20 ºC for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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