China Pharmaceutical Raw Material Pure API CAS 80214-83-1 Roxithromycin Powder/Roxithromycin for Antibacterial, Find details about China Roxithromycin Powder, Roxithromycin from Pharmaceutical Raw Material Pure API CAS 80214-83-1 Roxithromycin Powder/Roxithromycin for Antibacterial
Description:
CAS No.:80214-83-1
Other Names:Roxithromycin
MF:C41H76N2O15
EINECS No.:N/M
Place of Origin: Anhui,China (Mainland)
Type:Antipyretic Analgesics and NSAIDs, Immune Function Agents
Grade Standard:Medicine Grade
Usage:Animal Pharmaceuticals, Pharmaceutical intermediates
Purity:96%min
Appearance:White Powder
Standard:BP/EP
Shelf life:2 Years
Package:25 Kg/drum
Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss. Roxithromycin is available under several brandnames, for example, Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Tirabicin and Coroxin. Roxithromycin is not available in the United States. Roxithromycin has also been tested to possess antimalarial activity.
Mechanism:Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.
Specification:
Product Name | Water soluble roxithromycin |
Classification | Antibiotic and Antimicrobial Agents |
CAS NO. | 80214-83-1 |
EINECS No | 201-134-4 |
Specs | 97% |
Chemical Name | (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2-methoxyethoxy)methoxy]imino}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one. |
Physical and chemical properties
| Molecular Formula: C41H76N2O15 Molecular weight: 748.99 Structural Formula: Description: white or white crystalline powder
|
Application | Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss |
Package | 25kg/drum |
Storage | Keep in cool and dry place; 3 years. |
| Certificate of Analysis | ||
| Item | Specification | Result |
| Assay | 99% | 99.68% |
| Appearance | White powder | conforms |
| Odor | Characteristic | conforms |
| Taste | Characteristic | conforms |
| Particle Size | NLT 100% Through 80 mesh | conforms |
| Loss on Drying | <2.0% | 0.46% |
| Heavy metals | ||
| Total Heavy Metals | ≤10ppm | conforms |
| Arsenic | ≤3ppm | conforms |
| Lead | ≤3ppm | conforms |
| Microbiological Tests | ||
| Total Plate Count | ≤1000cfu/g | conforms |
| Total Yeast & Mold | ≤100cfu/g | conforms |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
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