Paclitaxel is a monomer diterpenoid compound extracted from the bark of Taxus, a natural plant. It is a complex secondary metabolite and the only known drug that can promote microtubule polymerization and stabilize the polymerized microtubule.Isotope tracers showed that paclitaxel only bound to the polymerized microtubules and did not react with the unpolymerized tubulin dimer.Cell exposure to paclitaxel Chemicalbook resulted in the accumulation of a large number of microtubules in cells, which interfered with various cell functions, especially stopping cell division during mitosis and blocking the normal division of cells.According to - clinical studies, paclitaxel is mainly suitable for ovarian cancer and breast cancer, and also has certain efficacy for lung cancer, colorectal cancer, melanoma, head and neck cancer, lymphoma and brain tumor.