Product Description                                                  

<sub>Product Name: Olopatadine hydrochloride;
Synonyms: OLOPATADINE HCL;OLOPATADINE HYDROCHLORIDE;OLOPATDINEHYDROCHLORIDE;OLOPATADINE HYDROCHLORIDE AND THE INTERMEDIATES;(Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride;OLAPATADINE HCL;Olopatadine Hydrochloride (150 mg);Olopatadin HCL;
CAS: 140462-76-6;
MF: C21H24ClNO3;
MW: 373.87;
Product Categories: Pharmaceutical material and intermeidates;APIs;Olopatadine;Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Opatanol, Pataday, Patanase, Allelock;API;
Melting point: 242-245 ºC;
storage temp.: Refrigerator;
Purity:99%
Apperance:white powderOlopatadine hydrochloride is an antihistamine (as well as anticholinergic and mast cell stabilizer), sold as a prescription eye drop manufactured by Alcon in one of three strengths: 0.7% solution or Pazeo in the US, 0.2% solution or Pataday (also called Patanol S in some countries), and 0.1% or Patanol (also called Opatanol in some countries). It is used to treat itching associated with allergic conjunctivitis (eye allergies). A decongestant nasal spray formulation is sold as Patanase, which was approved by the FDA on April 15, 2008. It is also available as an oral tablet;

It should not be used to treat irritation caused by contact lenses. The usual dose for Patanol is 1 drop in each affected eye 2 times per day, with 6 to 8 hours between doses. Both Pazeo and Pataday are dosed 1 drop in each eye daily.

There is potential for Olopatadine as a treatment modality for steroid rebound (red skin syndrome).</sub>

                                                 Application                                                          

_{Olopatadine is a potent, selective antagonist of the H1 histamine receptor (Ki = 16-41.1 nM), with much lower affinities for the H2 and H3 receptors (Ki = 43.4 and 172 μM, respectively). It blocks histamine-induced phosphoinositide turnover in isolated cells (IC50 = 9.5-39.9 nM) and prevents passive cutaneous anaphylaxis in rats (ED50 = 49 μg/kg) and anaphylactic bronchoconstriction in guinea pigs (ID50 = 30 μg/kg). Olopatadine is effective in treating allergic rhinitis and conjunctivitis. It also suppresses itch in patients with well-controlled chronic urticaria. In humans, this antihistamine does not cause cognitive or psychomotor impairment at therapeutic doses.}

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_{Xi'an Tian guangyuan Biotech Co.,Ltd.}

_{Tel: 86-29-86333380}

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<sub>We have more than 500 vendors, we could save your effort to serve customers with supplying all your needs!

1. We has 10 years' exporting experience in active pharmaceutical ingredient products.
Our professionaland thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

1> Any inquiries will be replied within 12 hours.
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                                       Company Information                                                 

<sub>XI'AN Tian Guangyuan Biotech Co.,Ltd.was founded in May 2003, is a professional animal and plant extracts modern and advanced enterprise object, chemical intermediates and active ingredients of natural active throughout the country, plant extracts industry, research and development, production, marketing and other areas have a strong strength.

The company is headquartered in the outskirts of Xi'an, under research and development center as well as analysis and testing center, comprehensive strength in the national forefront of the industry.
Companies rely on the wisdom and innovation of advanced technology, scientific management and all the staff and a good team spirit, will enable the company to develop a domestic industry with sik-class product quality and international competitiveness of enterprises.
Thank you for your interest in our products.</sub>

                                                       FAQ                                                                

_{1. Can I buy a sample for evaluation?} 

_{Yes, a small percentage of items are available for single-unit sample purchases online. To make it easier for our customers to locate these items, a separate section in our store will be created soon. For now, if an item offers samples, Click on the link to order the sample.}

_{2. How to make payment?} 

_{We accept payment by telegraphic transfer (T/T) and Western Union .}

_{3. How much does shipping cost?} 

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and ship-to country when you checkout and before you commit to the purchase. Generally, shipping to the UK and other Western European countries is slightly more expensive than to the USA. And shipping to  Asia is slightly less expensive than to the USA.}

_{4. Does the shipping cost cover local taxes, import duties, and other import-related costs?} 

_{The shipping cost does not cover any local taxes, import duties, customs clearance, or any other import-related costs levied by your government. The buyer is responsible for these import-related costs. Please check with your local customs office for more information.}

_{5. What shipping options do I have?} 

_{In our continued effort to offer value and flexibility to our customers, we will be offering four different options to deliver your order.}

_{1-200kg Carrier express(DHL/UPS/Fedex/EMS)} 

_{300kg-500kg by air}

_{6. How long is lead time?} 

_{We deliver goods within 3 days for small order, 7-10 days for bulk order.}