China High Quality Bulk Powder Sodium Deoxycholate 302-95-4, Find details about China Sodium Deoxycholate, Sodium Deoxycholic Acid from High Quality Bulk Powder Sodium Deoxycholate 302-95-4
Basic Information:
Product name:Sodium Deoxycholate
Specifications:98%
Appearence:White Powder
Assay of
Resource: Ox Bile
Solubility: Soluble in water, slightly soluble in anhydrous alcohol, insoluble in ether
Product Description:
In nature, sodium deoxycholate, which is referred to as a "secondary bile acid", is produced in the intestine from the salts of glycocholic and taurocholic acid (see cholic acid ) by the action of bacterial enzymes. Less than half of the sodium deoxycholate is absorbed by the intestine and is returned the liver where it is conjugated and released into the gall bladder.
Sodium deoxycholate is extracted from cattle bile(also known as "bovine bile" or "ox bile") , which is a by-product of the meat processing industry, in a high temperature alkaline process.
Function:
(1) Historically sodium deoxycholate was used as an intermediate for the production of corticosteroids, which have anti-inflammatory indications.
(2) It is used in the preparation and formulation of certain microbiological diagnostic media.
(3) An emerging use of sodium deoxycholate acid is as a biological detergent to lyse cells and solubilise cellular and membrane components.
(4) Popular anionic, bile-acid detergent for many laboratory uses
(5) Effective in disrupting and dissociating many types of protein interaction
(6) Useful for elution or regeneration of certain kinds of affinity columns
(7) It is most frequently used as a component of cell lysis buffers (e.g., RIPA buffer), but also has been used for liposome preparation, isolation of membrane proteins and lipids, preventing nonspecific binding in affinity chromatography and a cell culture media supplement.
FAQ
Application Area:
Uridine 5-Mophosphate Disodium are produced through the hydrolytic reaction from Ribonucleic acid(RNA) as raw material by enzymatic catalysis to form four kinds of nucleotides 5- 'AMP (adenosine-5'-monophosphate), 5'-GMP•2Na(guanosine-5'-monophosphate, disodium salt), 5'-CMP(cytidine-5'-monophosphate)-, 5'-UMP•2Na (uridine- 5'-monophosphate,Disodium salt) .By the chromatographic isolation, four kinds of separated 5'-nucleotide products with high purity can be obtained. These products can be widely applied in medicine, reagent, fine chemical industry, and additive of food fields etc.