High Quality 99% Purity Pharmaceutical Intermediate Gliclazide
Product Name: | Gliclazide |
Synonyms: | Gliclazide, BP;)-4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)-ure;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)urea;benzenesulfonamide,n-(((hexahydrocyclopenta(c)pyrrol-2(1h)-yl)amino)carbonyl;n-(4-methylbenzenesulfonyl)-n'-(3-azabicyclo(3.3.0)oct-3-yl)urea;Tetrabenzyl Voglibose HCl |
CAS: | 21187-98-4 |
MF: | C15H21N3O3S |
MW: | 323.41 |
EINECS: | 244-260-5 |
An N-(long-chain-acyl) ethanolamina that is the ethanolamide of palmitic (hexadecanoic) acid.Used in antiinflammatory.
What is Gliclazide ?
Gliclazide is an oral antihyperglycemic agent used for the treatment of diabetes mellitus type II. It belongs to the sulfonylurea class of insuln secretagogues, which stimulates β cells of the pancreas to release insulirn. Gliclazide binds to the β cell sulfonyl urea receptor (SUR1), further blocking the ATP sensitive potassium channels.
Function & Application1. Hypoglycemic effect: gliclazide is the second-generation oral sulfonylurea hypoglycemic agents. Its role is more than ten times stronger than tolbutamide. Mechanism of action is to stimulate pancreatic β cells to release insulrn, and then the high blood sugar drops. This may be because that sulfonylurea combines with β cell surface receptor, and increases the activation and simultaneously improves the sensitivity of outer periphery of the target tissue to insulrn.
2. It can reduce platelet aggregation and adhesion, and prevent fibrin depositing in the microvasculature.
3. It can lower cholesterol savings, and reduce plasma concentrations of arterial triphosphate glycerides and fatty acids. The role of the three not only can treat diabetes metabolic disorders, but also prevent and treat complications like the development and progression of diabetes-blood vessels, retinal, renal disease.Uses | 1. For adults with type 2 diabetes, diabetes associated with obesity or vascular lesions. 2. Hypoglycemic agents. It can be used for the treatment of non-insulrn dependent diabetes mellitus. 3. Hypoglycemic agents, non-insulrn dependent diabetes mellitus. The above information is edited by the Chemicalbook of Ge Qian. |
Side effects | Occasional mild nausea, vomiting, abdominal pain, constipation, diarrhea, erythema, urticaria, thrombocytopenia, neutropenia, anemia. Most adverse reactions disappeared after withdrawal. |
1) For the packaging of solid products, we have three types of packaging based on value: fiber drum, carton, plastic woven bag/PP bag.
2) Usually , fiber drum and bag is weight of 25kg ,Carton is weight of 20kg.
3) By DHL, Fedex, UPS, by Sea or by Air, accoring to client's request.
Client's request
Dalian Sinobio Chemistry Co.,Ltd_was established in 2011 and located in beautiful costal city Dailan Liaoning Province. we can enjoy convenient transportation by all logistic ways. Sinobio cooperated with Dalian university of technology, who has 2 production sites: one located in Lanzhou city , Gan Su province who mainly produce biocides and pharmaceutical related. Another located in Fuzhou city,Jiangxi province .It was founded in 2013 with abundant financial resources.
As a professional agrochemical and it's intermediates products' supplier, they have excellent teams who focus on product development & design, quality control & inspection and company running. In order to supply the qualified products and services, we have built a modern quality management system which is in strict accordance with international standards. Our factory has got ISO9001&ISO14001 certificates.
Adhering to the business principle of mutual benefits, we have had a good reputation among our customers because of our perfect services, quality products and competitive prices. We warmly welcome customers from at home and abroad to cooperate with us for common success.
Q1: Can I get samples?
A: Yes, we can supply free sample, you pay for the freight charge only.
Q2: How to pay?
A: PI will be sent firstly after our aligned products specification. Payment by Paypal , T/T, Western Union,LC, are ok.
Q3: How is your MOQ?
A: Normally speaking, our MOQ is 1kg. But we can also accept less quantity such as 100g on the condition that sample charge is100% paid.
Q4: How can you guarantee the quality of your products ?
1. Our staff are all experienced in chemical products or related major background, they are well trained before quotation.
2. Free sample or pre-shipment sample are available for our new cooperation before you place commercial order. We are sure the same specification commercial products as sample to customers
3. Third Party Inspection like SGS can be arranged according to your requirement before shipping.
4. On-Spot QC in our APPROVED associated production bases with necessary certification like GMP, ISO etc.
Q5: If you still have questions, to contact with us. we-chat: sunrenping5945