China Pharmaceutical Chemical Raw Powder CAS 797-63-7 Levonorgestrel, Find details about China Levonorgestrel Raw Powder, Norgestrel from Pharmaceutical Chemical Raw Powder CAS 797-63-7 Levonorgestrel
Product name:Levonorgestrel Powder |
Other Name: Norgestrel,[18,19-Dinorpregn-4-en-20-yn-3-one-13-ethyl-17-hydroxy-,(17.α.)-(-)-] |
Appearance:White Powder |
CAS:797-63-7 |
M.F:C21H28O2 |
M.W.:312.45 |
Specification:99% |
Levonorgestrel is a second-generation progestin and is the most widely prescribed contraceptive progestin worldwide. It has high progestational and androgenic effects. Levonorgestrel negatively affects serum lipoproteins.
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ITEM | SPECIFICATION | RESULT | METHOD |
Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
Specific Optical | -2.4°~ -2.8° | -2.72° | |
Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
pH | 4.5~7.0 | 5.10 | |
Related substance | Spot not bigger than standard solution spot | No spot | TLC |
Water Content | ≤2% | 0.26% | KF |
Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
Applied in pharmaceutical field, Levonorgestrel can be used as an active ingredient in some hormonal contraceptives, including combined oral contraceptive pills, progestogen only pills, emergency contraceptive pills, intrauterine systems and contraceptive implants;
Levonorgestrel is safe, tolerated and effective in emergency contraception in woman;
Levonorgestrel also can be used for the treatment of menopausal and postmenopausal disorders and alone or in combination with other hormones as an oral contraceptive.