High Quality Saxagliptin CAS 361442-04-8

China High Quality Saxagliptin CAS 361442-04-8, Find details about China Saxagliptin, 361442-04-8 from High Quality Saxagliptin CAS 361442-04-8

Model NO.
API
Package
Zip Bag and Alumium Bag
Trademark
Huichem
Specification
100g/bag 1kg/bag 25kgs/drum
Origin
China
Model NO.
API
Package
Zip Bag and Alumium Bag
Trademark
Huichem
Specification
100g/bag 1kg/bag 25kgs/drum
Origin
China
High quality Saxagliptin cas 361442-04-8
 

Product Description

Introduction:
The U.S. FDA approved eribulin mesylate (also referred to as E7389) in November 2010 for the treatment of metastatic breast cancer (MBC) for patients who previously received at least two chemotherapeutic regimens for late-stage disease. Eribulin is a synthetic analog of the marine natural product halichondrin B, which is isolated from the sea sponge Halichondria okadai. Eribulin retains most of the structural elements that constitute the right hand side of halichondrin B; structure-activity relationship (SAR) studies suggested that the antitumor activity of halichondrin B resides in that part of the molecule . Eribulin is a microtubule inhibitor that binds close to the vinca-binding site of tubulin. Unlike most tubulin inhibitors like taxanes, epothilones, and vinca alkaloids that inhibit microtubule dynamic instability by changing tubulin addition and loss parameters, eribulin's effects on dynamic instability are novel in that eribulin inhibits the growth phase of microtubules without affecting the shortening phase by binding to microtubule plus ends.

Function:
Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration an d has a pharmacokinetic profile compatible with once daily dosing .

Application:

Shacketine is a type 2 diabetes drug that can stimulate the pancreas to produce more in*sulin after the meal. It was reached by the cooperation of AstraZeneca and Bristol-Myers Squibb Company and belongs to DPP-IV inhibitor. It plays the role through inhibiting GLP-l degradation. GLP-I is the hormones naturally produced in the intestine after taking food. It can regulate the secretion of in*sulin and strengthen the utilization of glucose in the peripheral tissues. The single medication of Shacketine can improve blood glucose control and the combined medication of Shacketine with metformin, sulfonylurea and thiazolidinediones can enhance curative effect. It leads to low risk of hypoglycemia and its adverse reactions are similar to placebo, showing better tolerance .

On July 31, 2009, Shakleitine tablets , a new drug of type 2 diabetes, jointly researched and developed AstraZeneca and Bristol-Myers Squibb was approved by the US FDA. It can be taken once a day to treat type 2 diabetes combined with controlling Diet and exercise. The most common side effects are upper respiratory tract infections, urinary tract infections and headaches. And other side effects include allergic reactions, such as rash and urticaria .

Product Parameters

 

High Quality Saxagliptin CAS 361442-04-8
Product nameSaxagliptin
CAS No.361442-04-8
Molecular FormulaC18H25N3O2
Purity99%
AppearanceWhite or almost white powder
PackageAluminum Bag;Drums
Shelf life 2 years

 

Packaging & Shipping

High Quality Saxagliptin CAS 361442-04-8
By ExpressBy AirBy Sea
Suitable for under 50kgSuitable for more than 50kgSuitable for more than 500kg
Fast: 3-7 daysFast: 3-7 daysSlow: 3-10 days
High costMedium costMedium cost
Door to door serviceDoor to door servicePort to port service
 

Customized Package Is Available.

We will always do our best to utilize the quickest and most affordable way for customers to receive orders.
And follow up with customers via email for all shipment details as well as updated track information until it arrives without damage.

 

Certifications

High Quality Saxagliptin CAS 361442-04-8

Company Profile

Shanghai HuiRui Chemical Technology Co., Ltd.(HuiCHem) is a high-tech enterprise engaged in the area of health care & nutrition. HuiChem have been working closely with our customers we deliver products and solutions that create value and competitive advantage while positively impacting the world we live in, as well as attentive service for the purpose to meet the demand of customers, spare no effort to create value for customers.

High Quality Saxagliptin CAS 361442-04-8
HuiChem is now headquartered in Shanghai, and has offices in Jiangsu, Shandong, Anhui and HongKong. Its Shanghai headquarters has nearly 2000 square meters of operation premises, including a total of over 1500 square meters of synthesis laboratories and more than 200 square meters of analysis laboratories (equipped with AAS, LC-MS, FTIR, NMR and other basic test equipment). We have set up two pilot scale laboratories, which lay speedy and stable foundation for process amplification and production of superior products. Besides, we have partner factories that are responsible for the commercial production in Jiangsu Province and Shandong Province. All of those, ensuring growing customer demand and smooth commercial production. We have been certified ISO9001:2008 and ISO14001:2004. The company has established good cooperative relationships with Shanghai Institute of Organic Chemistry of Chinese Academy of Sciences(SIOC), Shanghai Institute of Materia Medica (SIMM), University of Science and Technology of China and Fudan University, and carried out a variety of creative R&D cooperation activities. 

High Quality Saxagliptin CAS 361442-04-8
We attach great importance to technical innovation and follow the latest dynamic of discovery and development to research and develop new products relying on advanced technology of synthetic chemistry, medicinal chemistry, biochemistry and analytical chemistry. We also pay attention to introduce and foster professional and technical personnel, the company has a group of vigorous and well-trained employees, and strong technical R&D forces. HuiChem has established a new system covering research and development, production and sales. Based on advanced equipment and strict management, always pursue the "open, inclusion, innovation, sharing" business philosophy, creating a win-win cooperation platform.
Everything originates from innovation. HuiChem combines the power of science and the passion of innovation. We believe to connect chemistry and innovation with the principles of sustainability to create a healthy life.

Exhibition

High Quality Saxagliptin CAS 361442-04-8

Our Advantages

Service:
1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.


Advantages:
1. Faster delivery: Sample order in stock and 3-7 days for bulk production.
2. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
3. After-Sale Service: 
1)International Authorized Third-Party Test For The Products You Demand. 
2)60 Days Warranty of quality of goods.

FAQ

Q1. How does your factory control quality?


All the raw material purchasing and production quality control are strictly following the ISO9001: 2008 management system. Besides, the full-featured detection equipment and GMP quality management system to provide the strongest guarantee for high quality product. We can provide our customers the detailed test report for the quality evaluation before the sample.

Q2. What's your main markets? 
North America, Europe, Asia, etc.

Q3. What is your delivery term and delivery period? 
We accept FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you. The sample within 3 days, and bulk order within 5 days.

Q4. What is your package?
Powder: PE bag, glass bottle or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
Liquid: glass bottle or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
Bulk order: Fiber drum or steel drum.

Q5. What is the payment term? 
We can accept T/T, Western Union, L/C and bank transfer.

Q6. Will you supply samples for test the quality? 
We'd like to offer our customers the free samples for the quality evaluation for most products, but the shipping cost is borne by customers.