High Quality Carboplatin with Good Price (CAS41575-94-4)
Quick Details:
Product Name | Carboplatin |
CAS | 41575-94-4 |
Quality Standard | EP/USP |
MOQ | 100 g |
Product Description:
Carboplatin is a second generation potent platinum-based antineoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of carboplatin was inspired from the efficacy of its progenitor, Cisplatin (sc-200896), the first of this class of antineoplastic agents. Carboplatin displays potent antitumor activity and lower nephrotoxicity than Cisplatin (sc-200896). The action of this group of platinum-based compounds is primarily attributed to DNA adduct formation, however, these molecules also bind other biological molecules, including enzymes, which might play a role in their mechanism of action.
COA: ITEMS | SPECIFICATIONS | RESULTS |
Appearance | White crystalline powder, soluble in water, very slightly soluble in e and in alcohol | Conforms |
Identification | IR | Conforms |
Appearance of solution | Solution is clear and colorless | Conforms |
Acidity | To 10ml of solution S1 add 0.1ml of phenolphthalein solution R1,the solution is colourless,not more than 0.7 ml of 0.01Me is required to change the colour of the indicator to pink | Conforms |
PH | 5.0~7.0 | 6.3 |
Loss on drying | ≤05% | 0.08% |
Residue on Ignition | ≤0.3% | 0.3% |
Transmittance | ≥97% | 97.2% |
Water-insoluble matter | ≤0.5% | 0.21% |
Limit of 1,1-cyclobutane- dicarboxylic acid | ≤0.5% | N.D |
Chromatographic purity: Individual impurity: All impurities: | ≤0.25% ≤0.5% | 0.077% 0.19% |
Platinum content | 52.0% - 53.0% | 52.33% |
Chlorides | ≤100ppm | Conforms |
Ammonium | ≤100ppm | Conforms |
Silver | ≤10ppm | Conforms |
Soluble barium | ≤10ppm | Conforms |
Assay | 98.0%-102.0% | 99.2% |
Conclusiion | This product complied with the standard of USP |
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