Factory Price High Purity Raw Powder Treat Acne Skin Beauty Isotretinoin CAS 4759-48-2

Name: Isotretinoin
English synonym: Tretinoin Impurity 1
CAS Number: 4759-48-2
Molecular formula: C20H28O2
Molecular weight: 300.44
EINECS number: 225-296-0

Melting point: 172-175°C(lit.)
Boiling point: 381.66°C(rough estimate)
Density: 1.0597(rough estimate)
Refractive index: 1.4800(estimate)
Storage conditions: -20°C
Solubility: Practically insoluble in water, slightly soluble in ethanol (96percent). It is sensitive to air, heat and light, especially insolution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use fresh lyprepared solutions.
Acidity coefficient (pKa): 4.76±0.33(Predicted)
Form: Fine Crystalline Powder
Color: Yellow-orange to orange
Water solubility: insoluble
Maximum wavelength (λmax): 354nm(EtOH)(lit.)
Merck: 14,5228
Stability: Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
Isotretinoin is an effective drug for the treatment of acne. It plays a role in the four stages of the onset of acne and prevents the formation of acne lesions:
Inhibit the secretion of sebaceous glands;
Inhibit the growth of Acne bacillus;
Inhibit the hyperplasia of sebaceous glands;
Anti-inflammatory effect.