For mild diabetes. It is mainly used for non-insulin-dependent diabetes mellitus, in which obese patients can be used as the drug of choice, and insulin-dependent diabetes mellitus can also be used in combination with insulin. It is effective in cases where certain sulfonylureas are ineffective.
This product is a biguanide oral hypoglycemic agent. It has a variety of mechanisms of action, including delaying the uptake of glucose from the gastrointestinal tract, increasing the utilization of peripheral glucose by increasing the sensitivity of insulin, and inhibiting excessive gluconeogenesis of the liver and kidney. This product does not reduce blood sugar levels in non-diabetic patients. During the patient's medication, the body weight is usually reduced, plasma cholesterol, triglyceride and pre-beta lipoprotein levels are reduced, and peripheral glucose metabolism can be improved.

This product has accurate hypoglycemic effect, and has no hypoglycemia reaction compared with sulfonylurea hypoglycemic drugs. It is effective for obese and non-obese non-insulin-dependent diabetics (NIDDM). It can reduce its basal blood glucose concentration ≥ 20% (generally 2mmol / L or 36mg / dl). It can improve oral or intravenous glucose tolerance test, and its hypoglycemic effect has nothing to do with blood glucose concentration, age, duration of disease, body weight and basal insulin level before use. It is often combined with sulfonylurea for patients who are not satisfied with sulfonylurea alone. Compared with sulfonylurea alone, it can lower blood sugar by more than 20%. Combined with insulin, it can reduce the amount of insulin.