99% Purity Artemisinin Powder Antimalarial Qinghausu CAS 63968 -64-9

China 99% Purity Artemisinin Powder Antimalarial Qinghausu CAS 63968-64-9, Find details about China Artemisinin, Artemisinin Powder from 99% Purity Artemisinin Powder Antimalarial Qinghausu CAS 63968-64-9

Model NO.
hupharma
Payment
Bitcoin/Wu/Mg/Wire Transfer
Minimum
10g
Delivery Time
1-3 Days
Shipping
Worldwide
Trademark
hupharma
Transport Package
Safe and Fast Delivery
Specification
10g, 100g, 1kg, 25kg
Origin
China
HS Code
2937290090
Model NO.
hupharma
Payment
Bitcoin/Wu/Mg/Wire Transfer
Minimum
10g
Delivery Time
1-3 Days
Shipping
Worldwide
Trademark
hupharma
Transport Package
Safe and Fast Delivery
Specification
10g, 100g, 1kg, 25kg
Origin
China
HS Code
2937290090
99% Purity Artemisinin Powder Antimalarial Qinghausu CAS 63968-64-9
99% Purity Artemisinin Powder Antimalarial Qinghausu CAS 63968-64-9
99% Purity Artemisinin Powder Antimalarial Qinghausu CAS 63968-64-9

Product Name: Artemisinin
Synonyms: 3,12-epoxy-12h-pyranol(4,3-j)-1,2-benzodioxepin-10(3h)-one,octahydro-3,6,9-tri;artemisiaannual.,extract;huanghuahaosu;octahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano(4,3-j)-1,2-benzodioxepin-10(;qinghausau;qinghausu;QHS;ARTEMISININ 99%
CAS: 63968-64-9
MF: C15H22O5
MW: 282.33
EINECS: 1806241-263-5
White to off-white crystalline powder
Uses: Active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial
Uses: An antimalarial agent that inhibits VEGF expression and NOS2.

Artemisinin is an antimalarial compound first isolated in pure form in 1972 by Chinese scientists from the herb qinghao (Artemisia annua). This herb (worm wood) has been used in Chinese traditional medicine to control fever for over 2000 years [1]. Artemisinin is a compound with a peculiar structure, low toxicity and high efficacy even in severe chloroquine resistant P. falciparum malaria. Unlike current antimalarial drugs which have a nitrogen-containing heterocylic ring system, it is a sesquiterpene lactone with an endoperoxide linkage. The endoperoxide linkage is essential for the antimalarial activity of the drug. Artemisinin has been shown to be a potent schizontocidal drug both in vitro and in experimental animal models, but it has no practical effect against the exoerythrocytic tissue phase, the sporozoites and the gametocytes[2].

The mechanism of action of artemisinin is not clearly understood. The drug selectively concentrates in parasitized cells by reacting with the intraparasitic hemin (hemozoin). In vitro this reaction appears to generate toxic organic free radicals causing damage to parasite membranes [2-4]. The derivatives of artemisinin are more potent than the parent drug and have apparently a similar mechanism of action


99% Purity Artemisinin Powder Antimalarial Qinghausu CAS 63968-64-9

99% Purity Artemisinin Powder Antimalarial Qinghausu CAS 63968-64-9