China Choline Glycerophosphate Powder CAS 28319-77-9, Find details about China Choline Glycerophosphate, Choline Glycerophosphate Powder from Choline Glycerophosphate Powder CAS 28319-77-9
Product Name | Choline glycerophosphate |
CAS NO | 28319-77-9 |
Molecular Weight | 257.221 |
Density | N/A |
Boiling Point | N/A |
Molecular Formula | C8H20NO6P |
Melting Point | -98ºC |
Flash Point | 11 °C |
L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have potential for the treatment of Alzheimer's disease and dementia.IC50 value:Target: Anti-ADAlpha-GPC rapidly delivers choline to the brain across the blood-brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter. It is a non-prescription drug in most countries due to its Generally Recognised As Safe (GRAS) status [1]. Studies have investigated its efficacy for cognitive disorders including stroke and Alzheimer's disease. An Italian multicentre clinical trial on 2,044 patients suffering from recent stroke were supplied alpha-GPC in doses of 1,000 mg/day for 28 days and 400 mg three times per day for the five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance [2].