1) The combination of levamlodipine besylate and the following drugs is safe: thiazide diuretics, β-receptor blockers, angiotensin-converting enzyme inhibitors, long-acting nitrate drugs, sublingual use Nitroglycerin, non-steroidal anti-inflammatory drugs, antibiotics and oral hypoglycemic drugs.
2) For healthy volunteers, the combination of this product with digo-xin did not change the chemicalbook blood concentration or renal clearance of digo-xin; when combined with cimetidine, the pharmacokinetics of this product did not change.
3) In vitro research data show that this product has no effect on the plasma protein binding rate of digo-xin, phenytoin, wa-rfarin or indomethacin.
4) For healthy male volunteers, this product is used in combination with Wa-rfarin, which will not affect the change of Wa-rfarin on prothrombin time.