China GMP Standard Nootropics Manufacturer Supply 99% Purity Galantamine Hydrobromide Powder CAS: 1953-04-4, Find details about China Galantamine Hydrobromide, Galantamine Hydrobromide Powder from China GMP Standard Nootropics Manufacturer Supply 99% Purity Galantamine Hydrobromide Powder CAS: 1953-04-4
Galantamine is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments, particularly those of vascular origin. It is an alkaloid that is obtained synthetically or from the bulbs and flowers of Galanthus Caucasicus (Caucasian snowdrop, Voronov's snowdrop), Galanthus woronowii (Amaryllidaceae) and related genera like Narcissus (daffodil)), Leucojum(snowflake) and Lycoris including Lycoris radiata (Red Spider Lily).
Galanthamine is natural extracted from lycoris radiate,is a tertiary alkaloid derived from snow drop and closely related species. It acts as a reversible competitive acetylcholinesterase (ACHE) inhibitor, while acts weaker on butyrylcholinesterse(BuChE). it is used in the treatment of disorders of the central nerbous system and may be used as an antidote to nonpolarizing muscle relaxants.Galanthamine hydrobromide is a white to almost white powder; sparingly soluble in water; insoluble chloroform, ether and alcohol .
1. Galanthamine Hydrobromide is mainly used in myasthenia gravis, poliovirus quiescent stage and sequela, also in polyneuritis, funiculitis and sensorimotor barrier caused by nervous system disease or traumatism;
2. Galanthamine Hydrobromide is also used in Alzheimer's disease, has the principal function for dement and dysmnesia caused by organic brain damage.
ITEMS | SPECIFICATION | RESULTS | |
BP2010 /EP6 | Appearance | crystalline powder | Conforms |
Melting point | About 205°C | 206.4°C~206.7°C | |
Identification | Meet the requirements | Conforms | |
Appearance of solution | Clear, not more intense than Y7 | Conforms | |
PH | 2.4~3.0 | 2.60 | |
Loss on drying | ≤0.5% | 0.04% | |
Sulphated ash | ≤0.1% | 0.01% | |
Heavy metals | ≤20 ppm | <20 ppm | |
Related substances | ≤0.25% | Conforms | |
Assay | 99.0%~101.0% | 99.8% | |
USP32 | Identification | Meet the requirements | Conforms |
Loss on drying | ≤0.5% | 0.04% | |
Residue on ignition | ≤0.1% | 0.01% | |
Heavy metals | ≤0.003% | <0.003% | |
Residue solvent - Ethanol | ≤0.5% | <0.04% | |
Chloride | 16.9%~17.6% | 17.1% | |
Assay | 98.0%~102.0% | 100.0% | |
Conclusion: The product complies with BP2010/USP32/EP6 standard |
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