China High Purity Lopinavir CAS 192725-17-0 for Antiviral, Find details about China Lopinavir, CAS 192725-17-0 from High Purity Lopinavir CAS 192725-17-0 for Antiviral
Product Name: Lopinavir
Synonyms: LOPINAVIR;(2s)-n-[(2r,4s,5s)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide;(aS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-Pyrimidineacetamide;A 157378.0;ABT 378;Aluviran;Koletr;134368
CAS: 192725-17-0
MF: C37H48N4O5
MW: 628.8
Melting point: 124-127°C
Boiling point: 924.1±65.0 °C
Storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
Description:
Lopinavir is a protease inhibitor that has been approved foruse in combination with ritonavir for patients with HIV whohave not responded to other treatment modalities. Lopinaviris used in excess over ritonavir. Ritonavir at amounts givenhas no antiretroviral activity, Ritonavir inhibits lopinavir'smetabolism by CYP3A4, causing a higher level of lopinavirin the system. The combination is the first protease inhibitorapproved for patients as young as 6 months of age.
Usage:
A selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral.
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